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  1. Link

    vmat2-antibody-ab191121.pdf

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Neuroscience Neurotransmitter Biogenic Amines Dopamine
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Anti-VMAT2 antibody (ab191121)

  • Datasheet
  • SDS
Submit a review Submit a question References (1)

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Western blot - Anti-VMAT2 antibody (ab191121)
  • Western blot - Anti-VMAT2 antibody (ab191121)
  • Western blot - Anti-VMAT2 antibody (ab191121)

Key features and details

  • Rabbit polyclonal to VMAT2
  • Suitable for: WB
  • Reacts with: Mouse, Rat, Human
  • Isotype: IgG

You may also be interested in

Protein
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Recombinant Human VMAT2 protein (ab112353)
 
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beta-Amyloid Peptide (1-40) (human) (ab120479)
Primary
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Anti-FOXP1 antibody (ab16645)

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Overview

  • Product name

    Anti-VMAT2 antibody
    See all VMAT2 primary antibodies
  • Description

    Rabbit polyclonal to VMAT2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.

  • Positive control

    • Human fetal brain, rat brain and mouse brain lysates.
  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 99% PBS, BSA
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Neuroscience
    • Neurotransmitter
    • Biogenic Amines
    • Dopamine
    • Neuroscience
    • Neurotransmitter
    • Biogenic Amines
    • Noradrenaline
    • Neuroscience
    • Neurotransmitter
    • Biogenic Amines
    • Serotonin / 5HT
    • Neuroscience
    • Neurotransmitter
    • Biogenic Amines
    • Histamine
    • Neuroscience
    • Neurotransmitter
    • Transporters
    • Dopamine
    • Neuroscience
    • Neurology process
    • Neurodegenerative disease
    • Parkinson's disease
    • Other
    • Neuroscience
    • Neurotransmission
    • Secretory Vesicles
    • Other
    • Neuroscience
    • Neurology process
    • Neurodegenerative disease
    • Other
    • Neuroscience
    • Neurotransmitter
    • Transporters
    • Other Transporters
    • Neuroscience
    • Processes

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Recombinant Protein

    • Recombinant Human VMAT2 protein (ab112353)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab191121 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
1/200. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).
Notes
WB
1/200. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).

Target

  • Function

    Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis.
  • Sequence similarities

    Belongs to the major facilitator superfamily. Vesicular transporter family.
  • Cellular localization

    Cytoplasmic vesicle membrane.
  • Target information above from: UniProt accession Q05940 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 6571 Human
    • Entrez Gene: 214084 Mouse
    • Entrez Gene: 25549 Rat
    • Omim: 193001 Human
    • SwissProt: Q05940 Human
    • SwissProt: Q8BRU6 Mouse
    • SwissProt: Q01827 Rat
    • Unigene: 596992 Human
    • Unigene: 268797 Mouse
    • Unigene: 361919 Mouse
    • Unigene: 9686 Rat
    see all
  • Alternative names

    • 1110037L13Rik antibody
    • 9330105E13 antibody
    • MGC120477 antibody
    • MGC120478 antibody
    • MGC26538 antibody
    • MGC90556 antibody
    • MNAT antibody
    • Monoamine neurotransmitter transporter antibody
    • Monoamine transporter antibody
    • OTTHUMP00000020576 antibody
    • SLC18A2 antibody
    • Solute carrier family 18 (vesicular monoamine) member 2 antibody
    • Solute carrier family 18 member 2 antibody
    • SVAT antibody
    • SVMT antibody
    • Synaptic vesicle amine transporter brain antibody
    • Synaptic vesicle monoamine transporter brain antibody
    • Synaptic vesicular amine transporter antibody
    • VAT 2 antibody
    • VAT2 antibody
    • Vesicle monoamine transporter type 2 antibody
    • Vesicle monoamine/H+ antiporter antibody
    • Vesicular amine transporter 2 antibody
    • Vesicular monoamine transporter 2 antibody
    • VMAT 2 antibody
    • VMAT2 antibody
    • VMAT2_HUMAN antibody
    see all

Images

  • Western blot - Anti-VMAT2 antibody (ab191121)
    Western blot - Anti-VMAT2 antibody (ab191121)
    Anti-VMAT2 antibody (ab191121) at 1/1000 dilution + Human fetal brain lysate at 10 µg

    Secondary
    Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

    Predicted band size: 56 kDa
    Observed band size: 56 kDa



    Blocking/Dilution buffer: 5% NFDM/TBST.

  • Western blot - Anti-VMAT2 antibody (ab191121)
    Western blot - Anti-VMAT2 antibody (ab191121)
    Anti-VMAT2 antibody (ab191121) at 1/200 dilution + Rat brain lysate at 10 µg

    Secondary
    Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

    Predicted band size: 56 kDa
    Observed band size: 56 kDa



    Blocking/Dilution buffer: 5% NFDM/TBST.

  • Western blot - Anti-VMAT2 antibody (ab191121)
    Western blot - Anti-VMAT2 antibody (ab191121)
    Anti-VMAT2 antibody (ab191121) at 1/1000 dilution + Mouse brain lysate at 10 µg

    Secondary
    Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

    Predicted band size: 56 kDa
    Observed band size: 56 kDa



    Blocking/Dilution buffer: 5% NFDM/TBST.

Protocols

  • Western blot protocols

Click here to view the general protocols

Datasheets and documents

  • SDS download

  • Datasheet download

    Download

References (1)

Publishing research using ab191121? Please let us know so that we can cite the reference in this datasheet.

ab191121 has been referenced in 1 publication.

  • Nyarko JNK  et al. Glycosylation States of Pre- and Post-synaptic Markers of 5-HT Neurons Differ With Sex and 5-HTTLPR Genotype in Cortical Autopsy Samples. Front Neurosci 12:545 (2018). PubMed: 30147642

Customer reviews and Q&As

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