Anti-VNN1 antibody (ab96171)
- Datasheet
- References (1)
- Protocols
Overview
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Product nameAnti-VNN1 antibody
See all VNN1 primary antibodies -
DescriptionRabbit polyclonal to VNN1
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Host speciesRabbit
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Tested applicationsSuitable for: WBmore details
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Species reactivityReacts with: Human
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Immunogen
Recombinant fragment, corresponding to a region within internal amino acids 232 - 427 of Human VNN1.
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Positive control
- H1299, HeLa or HepG2 cell lines.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol, 1.21% Tris, 0.75% Glycine -
Concentration information loading...
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PurityImmunogen affinity purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab96171 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | 1/500 - 1/3000. Predicted molecular weight: 57 kDa. |
Target
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FunctionAmidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.
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Tissue specificityWidely expressed with higher expression in spleen, kidney and blood. Overexpressed in lesional psoriatic skin.
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Sequence similaritiesBelongs to the CN hydrolase family. BTD/VNN subfamily.
Contains 1 CN hydrolase domain. -
Cellular localizationCell membrane.
- Information by UniProt
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Database links
- Entrez Gene: 8876 Human
- Omim: 603570 Human
- SwissProt: O95497 Human
- Unigene: 12114 Human
- Unigene: 720659 Human
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Alternative names
- HDLCQ8 antibody
- High density lipoprotein cholesterol level quantitative trait locus 8, included antibody
- Pantetheinase antibody
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Images
Protocols
References
This product has been referenced in:
- Povero D et al. Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells. Sci Signal 6:ra88 (2013). Neutralising ; Human . Read more (PubMed: 24106341) »