Overview

  • Product name
    Anti-VNN1 antibody
    See all VNN1 primary antibodies
  • Description
    Rabbit polyclonal to VNN1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within internal amino acids 232 - 427 of Human VNN1.

  • Positive control
    • H1299, HeLa or HepG2 cell lines.

Properties

Applications

Our Abpromise guarantee covers the use of ab96171 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 57 kDa.

Target

  • Function
    Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.
  • Tissue specificity
    Widely expressed with higher expression in spleen, kidney and blood. Overexpressed in lesional psoriatic skin.
  • Sequence similarities
    Belongs to the CN hydrolase family. BTD/VNN subfamily.
    Contains 1 CN hydrolase domain.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
    • Alternative names
      • HDLCQ8 antibody
      • High density lipoprotein cholesterol level quantitative trait locus 8, included antibody
      • Pantetheinase antibody
      • Pantetheine hydrolase antibody
      • Tiff66 antibody
      • V-1 antibody
      • Vanin 1 antibody
      • Vanin-1 antibody
      • Vannin 1 antibody
      • Vascular non inflammatory molecule 1 antibody
      • Vascular non-inflammatory molecule 1 antibody
      • VNN 1 antibody
      • VNN1 antibody
      • VNN1_HUMAN antibody
      see all

    Images

    • Western blot - Anti-VNN1 antibody (ab96171)
      Western blot - Anti-VNN1 antibody (ab96171)
      Anti-VNN1 antibody (ab96171) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

      Predicted band size: 57 kDa



      7.5% SDS PAGE

    References

    This product has been referenced in:
    • Povero D  et al. Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells. Sci Signal 6:ra88 (2013). Neutralising ; Human . Read more (PubMed: 24106341) »

    See 1 Publication for this product

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    1 Review or Q&A

    10
    Votes: Highest First

    Would like to try ab96171 with mouse samples.

    DISCOUNT CODE: ***
    Expiration date: February 13, 2013
    Value: $337

    This code will give you $337 off your next order before the expiration date. To redeem this offer, please submit an Abreview for ab96171 with mouse samples and includ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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