Anti-VNN1/Vanin-1 antibody (ab96171)

Submit a review Q&A (1)References (1)
Western blot - Anti-VNN1/Vanin-1 antibody (ab96171)

    Key features and details

    • Rabbit polyclonal to VNN1/Vanin-1
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

    Overview

    • Product name

      Anti-VNN1/Vanin-1 antibody
      See all VNN1/Vanin-1 primary antibodies

    • Description

      Rabbit polyclonal to VNN1/Vanin-1

    • Host species

      Rabbit

    • Tested applications

      Suitable for: WBmore details

    • Species reactivity

      Reacts with: Human

    • Immunogen

      Recombinant fragment corresponding to Human VNN1/Vanin-1 aa 232-427 (internal sequence).

    • Positive control

      • H1299, HeLa or HepG2 cell lines.

    • General notes

       This product was previously labelled as VNN1

       

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    Applications

    Our Abpromise guarantee covers the use of ab96171 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    WB 1/500 - 1/3000. Predicted molecular weight: 57 kDa.

    Target

    • Function

      Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.

    • Tissue specificity

      Widely expressed with higher expression in spleen, kidney and blood. Overexpressed in lesional psoriatic skin.

    • Sequence similarities

      Belongs to the CN hydrolase family. BTD/VNN subfamily.
      Contains 1 CN hydrolase domain.

    • Cellular localization

      Cell membrane.
    • Information by UniProt

    • Database links

      • Alternative names

        • HDLCQ8 antibody
        • High density lipoprotein cholesterol level quantitative trait locus 8, included antibody
        • Pantetheinase antibody
        • Pantetheine hydrolase antibody
        • Tiff66 antibody
        • V-1 antibody
        • Vanin 1 antibody
        • Vanin-1 antibody
        • Vannin 1 antibody
        • Vascular non inflammatory molecule 1 antibody
        • Vascular non-inflammatory molecule 1 antibody
        • VNN 1 antibody
        • VNN1 antibody
        • VNN1_HUMAN antibody
        see all

      Images

      • Western blot - Anti-VNN1/Vanin-1 antibody (ab96171)
        Western blot - Anti-VNN1/Vanin-1 antibody (ab96171)
        Anti-VNN1/Vanin-1 antibody (ab96171) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

        Predicted band size: 57 kDa



        7.5% SDS PAGE

      References (1)

      Publishing research using ab96171? Please let us know so that we can cite the reference in this datasheet.

      ab96171 has been referenced in 1 publication.

      • Povero D  et al. Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells. Sci Signal 6:ra88 (2013). Neutralising ; Human . PubMed: 24106341

      Customer reviews and Q&As

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      Question

      Would like to try ab96171 with mouse samples.

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      Answer

      DISCOUNT CODE: ***
      Expiration date: February 13, 2013
      Value: $337

      This code will give you $337 off your next order before the expiration date. To redeem this offer, please submit an Abreview for ab96171 with mouse samples and include this code in the “Additional Comments” section so we know the Abreview is for this promotion. Please remember that submission of the Abreview is sufficient for the discount code to become active. For more information on how to submit an Abreview, please visit the site: www.abcam.com/Abreviews.

      The code will be active once the Abreview has been submitted and can be redeemed in one of the following ways: 1) Call to place your order and mention the code to our customer service department; 2) Include the code in your fax order; 3) Place your order on the web and enter the promotional code.

      Any feedback that you can provide will be greatly appreciated, whether positive or negative. If you have any further questions, please do not hesitate to contact us. We look forward to receiving your Abreview and wish you luck with your research.

      The terms and conditions applicable to this offer can be found here: www.abcam.com/abtrial.

      Read More

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
      For licensing inquiries, please contact partnerships@abcam.com