Overview

  • Product name

  • Description

    Rabbit polyclonal to VPAC2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide aa 80-125 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    N FYSRPGNISK NCTSDGWSET FPDFIDACGY NDPEDESKIT FYILV


    Database link: P35000

  • Positive control

    • IHC-P: Human lung carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab216630 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

Target

  • Function

    This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C.
  • Tissue specificity

    Expressed in CD4+ T-cells, but not in CD8+ T-cells. Expressed in the T-cell lines Jurkat, PEER, MOLT-4, HSB, YT and Tsup-1, but not in the T-cell lines HARRIS and HUT 78.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 2 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Helodermin-preferring VIP receptor antibody
    • PACAP type III receptor antibody
    • PACAP-R-3 antibody
    • PACAP-R3 antibody
    • Pituitary adenylate cyclase-activating polypeptide type III receptor antibody
    • Vasoactive intestinal polypeptide receptor 2 antibody
    • VIP Receptor 2 antibody
    • VIP-R-2 antibody
    • Vipr2 antibody
    • VIPR2_HUMAN antibody
    • VPAC2 receptor antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed and paraffin embedded human lung carcinoma tissue labeling VPAC2 using ab216630 at 1/200, followed by secondary detection and DAB staining.

References

This product has been referenced in:

  • Li S  et al. VIP activates primordial follicles of rat through ERK-mTOR pathway during in tissue culture. Reproduction N/A:N/A (2019). Read more (PubMed: 30817320) »
See 1 Publication for this product

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