Key features and details
- Rabbit polyclonal to VPS37B
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-VPS37B antibody
DescriptionRabbit polyclonal to VPS37B
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
- Human colon tissue; RT4, U251 MG, Liver and Tonsil lysates.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab122450 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
|WB||Use a concentration of 0.04 - 0.4 µg/ml.|
FunctionComponent of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
Tissue specificityWidely expressed. Expressed in macrophages and lymphocytes.
Sequence similaritiesBelongs to the VPS37 family.
Contains 1 VPS37 C-terminal domain.
Cellular localizationLate endosome membrane. Recruited to the endosomal membrane in a VPS4A-dependent fashion.
- Information by UniProt
- ESCRT-I complex subunit VPS37B antibody
- hVps37B antibody
- Vacuolar protein sorting-associated protein 37B antibody
ab122450 has not yet been referenced specifically in any publications.