Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA
Concentration information loading...
PurityImmunogen affinity purified
Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Our Abpromise guarantee covers the use of ab40851 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.03 - 0.1 µg/ml. Predicted molecular weight: 39 kDa.|
|IHC-P||Use a concentration of 3 - 6 µg/ml.|
FunctionComponent of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
Sequence similaritiesBelongs to the VPS37 family.
Contains 1 VPS37 C-terminal domain.
Cellular localizationLate endosome membrane. Probably associates with membranes. Recruited to the plasma membrane by HIV-1.
- Information by UniProt
- 5730409F24Rik antibody
- AU042646 antibody
- ESCRT I complex subunit VPS37C antibody
Anti-VPS37C antibody (ab40851) at 0.03 µg/ml + Human Duodenum lysate (35µg protein in RIPA buffer).
Predicted band size: 39 kDa
Observed band size: 39 kDa
Primary incubation was 1 hour. Detected by chemiluminescence.
ab40851 at 3.8 µg/ml staining VPS37C in Human prostate tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
ab40851 has not yet been referenced specifically in any publications.