Overview

  • Product name

    W-5, calmodulin inhibitor
  • Description

    CaM inhibitor
  • Biological description

    CaM inhibitor (Ki = 11 μM, IC50 = 240 μM, CaM-dependent PDE activity). W-7 (ab143768), W-12 (ab143758) and W-13 analog. Shows antiproliferative effects. Inhibits photosynthesis in vivo.
  • CAS Number

    61714-25-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Egea J  et al. Nerve growth factor activation of the extracellular signal-regulated kinase pathway is modulated by Ca(2+) and calmodulin. Mol Cell Biol 20:1931-46 (2000). Read more (PubMed: 10688641) »
  • Giglioli-Guivarc'h N  et al. The Light-Dependent Transduction Pathway Controlling the Regulatory Phosphorylation of C4 Phosphoenolpyruvate Carboxylase in Protoplasts from Digitaria sanguinalis. Plant Cell 8:573-586 (1996). Read more (PubMed: 12239393) »
  • Serlin BS & Roux SJ Modulation of chloroplast movement in the green alga Mougeotia by the Ca2+ ionophore A23187 and by calmodulin antagonists. Proc Natl Acad Sci U S A 81:6368-72 (1984). Read more (PubMed: 11536594) »

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