Overview

  • Product name
  • Description
    Rabbit polyclonal to WAC
  • Host species
    Rabbit
  • Specificity
    At least two isoforms of WAC are known to exist; this antibody will detect the larger isoform.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A synthetic peptide, corresponding to an 19 amino acid peptide near the center of Human WAC (NP_057712).

  • Positive control
    • Human testis tissue lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab167120 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 71 kDa.

Target

  • Function
    Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription. Regulates the cell-cycle checkpoint activation in response to DNA damage.
  • Sequence similarities
    Contains 1 WW domain.
  • Post-translational
    modifications
    Phosphorylated on tyrosine residues.
  • Cellular localization
    Nucleus speckle. Nucleus. In distinct nuclear speckles. Colocalizes with pre-mRNA processing complexes.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1110067P07Rik antibody
    • BA48B24 antibody
    • BA48B24.1 antibody
    • BM 016 antibody
    • FLJ31290 antibody
    • KIAA1844 antibody
    • MGC10753 antibody
    • OTTHUMP00000019380 antibody
    • OTTHUMP00000019382 antibody
    • PRO1741 antibody
    • wac antibody
    • WAC_HUMAN antibody
    • WW domain containing adapter protein with coiled coil antibody
    • WW domain containing adaptor with coiled coil antibody
    • WW domain-containing adapter protein with coiled-coil antibody
    • Wwp4 antibody
    see all

Images

  • Anti-WAC antibody (ab167120) at 1 µg/ml + Human testis tissue lysate at 15 µg

    Predicted band size: 71 kDa

References

ab167120 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab167120.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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