The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Predicted molecular weight: 50 kDa.
Acts as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting.
Belongs to the WASH1 family. Contains 1 WH2 domain.
Early endosome membrane. Recycling endosome membrane. Localization to the endodome membrane is mediated via its interaction with FAM21.