Overview

  • Product name

    WAY-200070, ERbeta agonist
  • Description

    Potent, selective ERβ agonist
  • Biological description

    Potent, selective estrogen receptor β (ERβ) agonist (EC50 values are 2.3 and 155 nM for ERβ and ERα respectively). Antianxiolytic and antidepressive activity. Active in vivo.
  • Purity

    > 98%
  • CAS Number

    440122-66-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Hughes ZA  et al. WAY-200070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agent. Neuropharmacology 54:1136-42 (2008). Read more (PubMed: 18423777) »
  • Harris HA Estrogen receptor-beta: recent lessons from in vivo studies. Mol Endocrinol 21:1-13 (2007). Read more (PubMed: 16556737) »
  • Malamas MS  et al. Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands. J Med Chem 47:5021-40 (2004). Read more (PubMed: 15456246) »

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