Anti-WDHD1 antibody [20G10] (ab67341)
- Datasheet
- References (1)
- Protocols
Overview
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Product name
Anti-WDHD1 antibody [20G10]
See all WDHD1 primary antibodies -
Description
Mouse monoclonal [20G10] to WDHD1 -
Host species
Mouse -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
A recombinant fragment from the C-terminal of the human protein
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
20G10 -
Isotype
IgG2a -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab67341 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use at an assay dependent concentration. Predicted molecular weight: 126 kDa. | |
| IHC-P | Use a concentration of 15 µg/ml. |
Target
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Relevance
The protein WDHD1 contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. -
Cellular localization
Nuclear; nucleoplasm. -
Database links
- Entrez Gene: 11169 Human
- Entrez Gene: 218973 Mouse
- Omim: 608126 Human
- SwissProt: O75717 Human
- SwissProt: P59328 Mouse
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Alternative names
- Acidic nucleoplasmic DNA binding protein 1 antibody
- And 1 antibody
- And1 antibody
see all
Images
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![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-WDHD1 antibody [20G10] (ab67341)](https://www.abcam.com/ps/products/67/ab67341/Images/ab67341-81446-anti-wdhd1-antibody-20g10-immunohistochemistry.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-WDHD1 antibody [20G10] (ab67341)ab67341, at 15µg/ml, staining WDHD1 in human kidney cells by immunohistochemistry using formalin-fixed, paraffin-embedded tissue.
Datasheets and documents
References
This product has been referenced in:
- Moiseeva T et al. ATR kinase inhibition induces unscheduled origin firing through a Cdc7-dependent association between GINS and And-1. Nat Commun 8:1392 (2017). Read more (PubMed: 29123096) »
