Overview

  • Product name
    Anti-WDHD1 antibody [20G10]
    See all WDHD1 primary antibodies
  • Description
    Mouse monoclonal [20G10] to WDHD1
  • Host species
    Mouse
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    A recombinant fragment from the C-terminal of the human protein

Properties

Applications

Our Abpromise guarantee covers the use of ab67341 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 126 kDa.
IHC-P Use a concentration of 15 µg/ml.

Target

  • Relevance
    The protein WDHD1 contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms.
  • Cellular localization
    Nuclear; nucleoplasm.
  • Database links
  • Alternative names
    • Acidic nucleoplasmic DNA binding protein 1 antibody
    • And 1 antibody
    • And1 antibody
    • WD repeat and HMG box DNA binding protein 1 antibody
    • WDHD 1 antibody
    see all

Images

  • ab67341, at 15µg/ml, staining WDHD1 in kidney cells by immunohistochemistry using formalin-fixed, paraffin-embedded tissue.

References

This product has been referenced in:
  • Moiseeva T  et al. ATR kinase inhibition induces unscheduled origin firing through a Cdc7-dependent association between GINS and And-1. Nat Commun 8:1392 (2017). Read more (PubMed: 29123096) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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