WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The WDR11 gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.
Membrane; Single-pass membrane protein, Cytoplasmic and Nuclear
Bromodomain and WD repeat containing protein 2 antibody
Bromodomain and WD repeat domain containing 2 antibody
Bromodomain- and WD repeat-containing protein 2, formerly antibody
BRWD2, formerly antibody
WD repeat containing protein 11 antibody
WD repeat containing protein 15 antibody
WD repeat domain 11 antibody
WD repeat domain 15 antibody
WDR 11 antibody
Western blot - Anti-WDR11 antibody (ab175256)
Anti-WDR11 antibody (ab175256) at 1/100 dilution + mouse testis tissue lysate at 15 µg
Predicted band size: 137 kDa
Flow Cytometry - Anti-WDR11 antibody (ab175256)
Flow cytometry analysis of 293 cells labeling WDR11 (green, right histogram), using ab175256 at a 1/10 dilution, and negative control cells (blue, left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.