Anti-WDR19 antibody (ab222908)
Key features and details
- Rabbit polyclonal to WDR19
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-WDR19 antibody
See all WDR19 primary antibodies -
Description
Rabbit polyclonal to WDR19 -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IF, IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human WDR19 aa 1-250.
Database link: Q8NEZ3 -
Positive control
- IHC-P: Human liver cancer and placenta tissues. ICC/IF: A549 cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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Purity
Protein G purified -
Purification notes
Purity >95% -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab222908 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ICC/IF |
1/50 - 1/200.
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IHC-P |
1/20 - 1/200.
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Notes |
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ICC/IF
1/50 - 1/200. |
IHC-P
1/20 - 1/200. |
Target
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Function
Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport (PubMed:20889716). Involved in cilia function and/or assembly (By similarity). Associates with the BBSome complex to mediate ciliary transport. -
Tissue specificity
Some isoforms are tissue-specific. Highly expressed in the prostate. Lower expression in the cerebellum, pituitary gland, fetal lung, and pancreas. In normal prostate, expressed in both basal and luminal epithelial cells. No expression detected in fibromuscular stromal cells, endothelial cells, or infiltrating lymphocytes. Uniformed expression in prostate adenocarcinoma cells. -
Involvement in disease
Cranioectodermal dysplasia 4
Short-rib thoracic dysplasia 5 with or without polydactyly
Nephronophthisis 13
Senior-Loken syndrome 8 -
Sequence similarities
Contains 6 TPR repeats.
Contains 6 WD repeats. -
Developmental stage
Expressed in fetal lung. -
Cellular localization
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium, photoreceptor outer segment. Localizes to photoreceptor connecting cilia, to the base of motile cilia in brain ependymal cells and to the base of and along primary cilia in kidney cells. - Information by UniProt
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Database links
- Entrez Gene: 57728 Human
- Omim: 608151 Human
- SwissProt: Q8NEZ3 Human
- Unigene: 438482 Human
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Alternative names
- DYF 2 antibody
- DYF2 antibody
- FLJ23127 antibody
see all
Images
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A549 (human lung carcinoma cell line) cells stained for WDR19 (green) using ab222908 at 1/100 dilution in ICC/IF. Secondary: Alexa Fluor 488® conjugated Goat Anti-Rabbit IgG (H+L).
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Paraffin-embedded human liver cancer tissue stained for WDR19 using ab222908 at 1/100 dilution in immunohistochemical analysis.
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Paraffin-embedded human placenta tissue stained for WDR19 using ab222908 at 1/100 dilution in immunohistochemical analysis.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab222908 has not yet been referenced specifically in any publications.