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ab22512 has been referenced in 21 publications.

  • Neilsen BK  et al. WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage. BMC Cancer 18:673 (2018). PubMed: 29925347
  • Vilhais-Neto GC  et al. The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry. Nat Commun 8:728 (2017). PubMed: 28959017
  • Alicea-Velázquez NL  et al. Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes. J Biol Chem 291:22357-22372 (2016). PubMed: 27563068
  • Shinsky SA  et al. Biochemical Reconstitution and Phylogenetic Comparison of Human SET1 Family Core Complexes Involved in Histone Methylation. J Biol Chem N/A:N/A (2015). PubMed: 25561738
  • Vulto-van Silfhout AT  et al. Variants in CUL4B are associated with cerebral malformations. Hum Mutat 36:106-17 (2015). PubMed: 25385192
  • Zhou P  et al. Mixed lineage leukemia 5 (MLL5) protein regulates cell cycle progression and E2F1-responsive gene expression via association with host cell factor-1 (HCF-1). J Biol Chem 288:17532-43 (2013). PubMed: 23629655
  • Kim K  et al. Gene dysregulation by histone variant H2A.Z in bladder cancer. Epigenetics Chromatin 6:34 (2013). PubMed: 24279307
  • Chen CY  et al. Rescue of the genetically engineered Cul4b mutant mouse as a potential model for human X-linked mental retardation. Hum Mol Genet 21:4270-85 (2012). Mouse . PubMed: 22763239
  • Xie L  et al. KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription. EMBO J 30:1473-84 (2011). WB ; Mouse . PubMed: 21448134
  • Benedikt A  et al. The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures. Leukemia 25:135-44 (2011). WB ; Human . PubMed: 21030982
  • Woo AJ  et al. Role of ZBP-89 in human globin gene regulation and erythroid differentiation. Blood 118:3684-93 (2011). PubMed: 21828133
  • Nakagawa T & Xiong Y X-linked mental retardation gene CUL4B targets ubiquitylation of H3K4 methyltransferase component WDR5 and regulates neuronal gene expression. Mol Cell 43:381-91 (2011). WB . PubMed: 21816345
  • Koues OI  et al. Roles for common MLL/COMPASS subunits and the 19S proteasome in regulating CIITA pIV and MHC class II gene expression and promoter methylation. Epigenetics Chromatin 3:5 (2010). ChIP ; Human . PubMed: 20181089
  • Liu H  et al. Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint. Nature 467:343-6 (2010). WB ; Human . PubMed: 20818375
  • Kotake Y  et al. DDB1-CUL4 and MLL1 mediate oncogene-induced p16INK4a activation. Cancer Res 69:1809-14 (2009). WB ; Human . PubMed: 19208841
  • Gu B  et al. Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J Cell Biol 185:811-26 (2009). WB ; Human . PubMed: 19487454
  • Jiang D  et al. Establishment of the winter-annual growth habit via FRIGIDA-mediated histone methylation at FLOWERING LOCUS C in Arabidopsis. Plant Cell 21:1733-46 (2009). PubMed: 19567704
  • Jacinto FV  et al. Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation. Oncogene 28:4212-24 (2009). PubMed: 19734945
  • Kim K  et al. Isolation and Characterization of a Novel H1.2 Complex That Acts as a Repressor of p53-mediated Transcription. J Biol Chem 283:9113-26 (2008). WB ; Human . PubMed: 18258596
  • Rampalli S  et al. p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation. Nat Struct Mol Biol 14:1150-6 (2007). PubMed: 18026121
  • Kinyamu HK & Archer TK Proteasome activity modulates chromatin modifications and RNA polymerase II phosphorylation to enhance glucocorticoid receptor-mediated transcription. Mol Cell Biol 27:4891-904 (2007). WB ; Human . PubMed: 17438138

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