Chromatin and Epigenetics: From Mechanisms to Execution
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Watch on demand the live sessions held on April 14 & 15, 2021
Description
Chromatin mechanisms and the epigenetic phenomena are two key pillars of modern biology. Watch this two part video series where the latest advances in the chromatin field are discussed, including the basic molecular mechanisms of transcriptional regulation, the complex epigenetic pathways in the development and the reprogramming of stem cells and organoids.
Session 1: How it works and how it looks
Webinar objectives
- Review RNA modifying enzymes and their role in cancer
- Discuss drugs against RNA modifying enzymes
- Describe how transcription factor NRF1 interacts with AUTS2 and directs AUTS2-ncPRC1.3 to target genes in the brain
Speakers
- Tony Kouzarides, University of Cambridge, UK
- Modifications of RNA: their function and role in cancer
- Timestamp: 07:26 - 36:20
- Danny Reinberg, New York University, USA
- PRC1-AUTS2 and brain development
- Timestamp: 38:40 - 1:13:06
Session 2: Single cells and their fates
Webinar objectives
- Review the biology of Rett Syndrome
- Discuss epigenetic editing in Rett Syndrome
- Describe symmetry breaking in gastruloid development
Speakers
- Rudolf Jaenisch, Massachusetts Institute of Technology, USA
- Biology of Rett Syndrome and therapeutic approaches
- Timestamp: 4:28 - 44:40
- Prisca Liberali, Friedrich Miescher Institute for Biomedical Research, Switzerland
- Symmetry breaking in gastruloid development
- Timestamp: 45:50 - 1:16:14
Contact
Have a question? Plese contact the Abcam Events Team.