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Knockout Cell Lines and Their Role in Confirming Antibody Specificity

​​This short webinar will cover the important role that knockout cells play in demonstrating antibodies’ specificity to their targets, including useful tips and tricks. 


Webinar Objectives:

  • ​ Gain a basic understanding of knockout cells
  • ​Learn about some of the pitfalls when using knockout cells
  • ​Discover how Abcam utilizes knockout cells in their catalog ​   ​


About the Presenter:

Will Howat leads Abcam’s global Imaging and Immunohistochemistry team as Director of Antibody Validation. Prior to joining Abcam in 2018, he worked at AstraZeneca as Team Leader of its Molecular Pathology Group, where his team developed biomarker assays for preclinical, Phase 1 and Phase 2 clinical trials. Before that he was at the Cancer Research UK’s Cambridge Institute, where he set up and ran the Histopathology/ISH core facility for 9 years. He has also worked at the Wellcome Sanger Institute on the Atlas of Protein Expression and was responsible for R&D in within the Immunohistochemistry group.

Will has a BSc (Hons) in Immunology & Pharmacology from the University of Strathclyde and a PhD in Pathology from the University of Southampton. His publications span key journals such as The Lancet, Nature, Science, Nature Genetics, American Journal of Pathology, and the Journal of Pathology.

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From one ,year, I am the team leader of the IHC team in Cambridge UK. The team is focused on the characterization and validation of antibody using immunohistochemistry techniques. I’ve joined Abcam about 5 years ago working as a Senior Scientist in the Imaging team. Before that I’ve always been working on academia. I was a Postdoc at the “Biotechnology Centre (BIOTEC) of the Technische Universität Dresden (TUD)” working on the generation of transgenic mice for a tamoxifen-induced, conditional expression of the Cre- recombinase in osteoclasts for the study of bone biology and osteoporosis. I’ve got my PhD in Italy (University of Palermo) with a project on the “Gene signature in patients affected by Autism disease”. 

Do you have any questions about this webinar? Contact us at events@abcam.com