Role of Chronic Inflammation in Risk for Neurodegenerative Disorders: Alzheimer’s Disease
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Join Dr. Malú Tansey, Professor of Neuroscience and Director of the Center for Translational Research in Neurodegenerative Disease at the University of Florida, Gainesville, USA, as she talks us through a new, alternative model for Alzheimer's disease.
Learn about genetic and environmental risk factors that combined increase disease risk, and how her research demonstrates a new therapeutic approach.
Webinar objectives:
- To understand the role of immune aging as a risk factor for age-related neurodegeneration.
- To outline how genetic predisposition and chronic inflammation may lead to innate immune dysfunction and offer an alternative view of Alzheimer’s disease pathogenesis.
- To summarize how targeting soluble Tumor Necrosis Factor could mitigate the effects of chronic inflammation associated with an obesogenic diet and its effects on metabolic dysregulation and how it may lower risk for the development of Alzheimer’s disease.
About the presenter:
Dr. Malú Tansey is Professor of Neuroscience and Director of the Center for Translational Research in Neurodegenerative Disease, University of Florida, USA. She is also the first endowed Chair at the Fixel Institute for Neurological Diseases.
Her lab studies the mechanisms underlying the role of immune and inflammatory responses in health and disease. This includes the role and regulation of the central and peripheral inflammatory and immune system responses that modulate both gene-environment and gut-brain axis interactions. Understanding such interactions might help determine risk related to the development and progression of neurodegenerative diseases such as Parkinson’s disease, Alzheimer’s disease and related dementias, as well as neuropsychiatric diseases including depression.
Dr. Malú Gámez Tansey obtained her BS/MS in biological sciences from Stanford University, California, USA, and her PhD in physiology from The University of Texas Southwestern Medical Center, Dallas, USA. Following her post-doctoral training at Washington University, St. Louis, USA, Dr. Tansey spent two years in the biotech sector in Los Angeles before returning to academia as an Assistant Professor of physiology at UT Southwestern. She became a tenured Associate Professor of physiology in 2008 at UT Southwestern, before moving to Emory University, Atlanta, USA, in 2009, where she became Professor of physiology and Director of the Center for Neurodysfunction and Inflammation.
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