Overview

  • Product name

  • Description

    Rabbit polyclonal to WFS1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from Human WFS1.

  • Positive control

    • Human brain tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab135893 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 100 kDa.

Target

  • Relevance

    WFS1 is a novel component of Wolfram syndrome, a rare form of juvenile diabetes. WFS1 plays an important role in maintaining homeostasis of the endoplasmic reticulum (ER) in the pancreas. It is normally up-regulated during insulin secretion, whereas inactivation of the protein can cause ER stress. Chronic ER stress is a major involvement in Wolfram syndrome.
  • Cellular localization

    Endoplasmic reticulum; endoplasmic reticulum membrane; multipass membrane protein
  • Database links

  • Alternative names

    • CTRCT41 antibody
    • DFNA14 antibody
    • DFNA38 antibody
    • DFNA6 antibody
    • DIDMOAD antibody
    • WFRS antibody
    • WFS antibody
    • WFSL antibody
    • Wolfram syndrome 1 (wolframin) antibody
    • Wolfram syndrome antibody
    • WOLFRAMIN antibody
    • wolframin ER transmembrane glycoprotein antibody
    see all

Images

  • Anti-WFS1 antibody (ab135893) at 1/500 dilution + Human brain tissue lysate at 30 µg

    Predicted band size: 100 kDa

References

ab135893 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab135893.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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