Key features and details
- Rabbit polyclonal to WFS1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-WFS1 antibody
See all WFS1 primary antibodies
DescriptionRabbit polyclonal to WFS1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide derived from Human WFS1.
- Human brain tissue lysate
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 0.88% Sodium chloride, 50% Glycerol
PBS without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab135893 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 100 kDa.|
RelevanceWFS1 is a novel component of Wolfram syndrome, a rare form of juvenile diabetes. WFS1 plays an important role in maintaining homeostasis of the endoplasmic reticulum (ER) in the pancreas. It is normally up-regulated during insulin secretion, whereas inactivation of the protein can cause ER stress. Chronic ER stress is a major involvement in Wolfram syndrome.
Cellular localizationEndoplasmic reticulum; endoplasmic reticulum membrane; multipass membrane protein
- CTRCT41 antibody
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ab135893 has not yet been referenced specifically in any publications.