Key features and details
- Rabbit polyclonal to WFS1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-WFS1 antibody
See all WFS1 primary antibodies
DescriptionRabbit polyclonal to WFS1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
Recombinant fragment corresponding to Human WFS1 aa 76-282. BC030130.
GTGPTKGDMEIPFEEVLERAKAGDPKAQTEVGKHYLQLAGDTDEELNSCT AVDWLVLAAKQGRREAVKLLRRCLADRRGITSENEREVRQLSSETDLERA VRKAALVMYWKLNPKKKKQVAVAELLENVGQVNEHDGGAQPGPVPKSLQK QRRMLERLVSSESKNYIALDDFVEITKKYAKGVIPSSLFLQDDEDDDELA GKSPEDL
Database link: O76024
- Human fetal heart and Human fetal muscle lysates.
FormLyophilized:Reconstitute in 200ul sterile H2O.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab176909 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/200 - 1/1000. Detects a band of approximately 100 kDa (predicted molecular weight: 100 kDa).|
RelevanceWFS1 is a novel component of Wolfram syndrome, a rare form of juvenile diabetes. WFS1 plays an important role in maintaining homeostasis of the endoplasmic reticulum (ER) in the pancreas. It is normally up-regulated during insulin secretion, whereas inactivation of the protein can cause ER stress. Chronic ER stress is a major involvement in Wolfram syndrome.
Cellular localizationEndoplasmic reticulum; endoplasmic reticulum membrane; multipass membrane protein
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ab176909 has not yet been referenced specifically in any publications.