Key features and details
- JAK3 inhibitor
- CAS Number: 188829-39-2
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameWHI-P131 hydrochloride, JAK3 inhibitor
Cell-permeable Janus kinase 3 (JAK3) inhibitor (IC50 values of 9.1 µM and 78 µM for human and mouse recombinant proteins respectively). Selective versus JAK1, JAK2, SYK, BTK and LYN tyrosine kinases.
Chemical name4-[(6,7-Dimethoxyquinazolin-4-yl)amino]phenol hydrochloride
Storage instructionsShipped at room temperature. Store at -20°C.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab142126 has not yet been referenced specifically in any publications.