Probable histone methyltransferase (By similarity). May act as a transcription regulator that binds DNA and suppresses IL5 transcription.
Involvement in disease
Note=A chromosomal aberration involving WHSC1 is a cause of multiple myeloma tumors. Translocation t(4;14)(p16.3;q32.3) with IgH. Note=WHSC1 is located in the Wolf-Hirschhorn syndrome (WHS) critical region. WHS results from by sub-telomeric deletions in the short arm of chromosome 4. WHSC1 is deleted in every case, however deletion of linked genes contributes to both the severity of the core characteristics and the presence of the additional syndromic problems.
Wolf Hirschhorn syndrome candidate 1 protein antibody
Wolf-Hirschhorn syndrome candidate 1 protein antibody
Western blot - Anti-WHSC1/NSD2 antibody (ab225625)
All lanes : Anti-WHSC1/NSD2 antibody (ab225625) at 0.04 µg/ml
Lane 1 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate at 50 µg Lane 2 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate at 15 µg Lane 3 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate at 5 µg
Developed using the ECL technique.
Predicted band size: 152 kDa
Exposure time: 30 seconds
has not yet been referenced specifically in any publications.
Publishing research using ab225625? Please let us know so that we can cite the reference in this datasheet.
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