WKYMVm, agonist for formyl peptide receptors FPR2 and FPR3 (ab141811)
- Datasheet
- References
Overview
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Product name
WKYMVm, agonist for formyl peptide receptors FPR2 and FPR3 -
Description
Selective agonist for formyl peptide receptors FPR2 and FPR3 -
Biological description
Selective agonist for formyl peptide receptors FPR2 and FPR3, expressed on immune cells. Induces calcium mobilization in FPR2-HL-60 and FPR3-HL-60 cells (EC50= 2 and 80 nM respectively). -
Purity
> 98% -
CAS Number
187986-17-0 -
Chemical structure
Properties
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Molecular weight
856.11 -
Molecular formula
C41H61N9O7S2 -
Sequence
WKYMVM (Modifications: C-terminal amide; Met-6 = D-Met) -
PubChem identifier
57340528 -
Storage instructions
The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Handling
After reconstitution the product is stable for up to one week at 4°C or three months at -20°C.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)C(C(=O)NC(CCSC)C(=O)N)NC(=O)C(CCSC)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CCCCN)NC(=O)C(CC2=CNC3=CC=CC=C32)N -
Source
Synthetic
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Research areas
References
This product has been referenced in:
- Christophe T et al. Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1/LXA4R, is not affected by lipoxin A4. Scand J Immunol 56:470-6 (2002). Read more (PubMed: 12410796) »
- Christophe T et al. The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. J Biol Chem 276:21585-93 (2001). Read more (PubMed: 11285256) »
- Baek SH et al. Identification of the peptides that stimulate the phosphoinositide hydrolysis in lymphocyte cell lines from peptide libraries. J Biol Chem 271:8170-5 (1996). Read more (PubMed: 8626507) »
