Anti-Wnt2/IRP antibody (ab150608)
Key features and details
- Rabbit polyclonal to Wnt2/IRP
- Suitable for: ELISA, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Wnt2/IRP antibody
See all Wnt2/IRP primary antibodies -
Description
Rabbit polyclonal to Wnt2/IRP -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins. -
Tested applications
Suitable for: ELISA, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Sheep, Rabbit, Horse, Chicken, Guinea pig, Hamster, Cow, Cat, Dog, Turkey, Pig, Chimpanzee, Ferret, Monkey, Baboon, Gorilla, Opossum, Common marmoset, Orangutan, Bat, Platypus, Elephant -
Immunogen
Synthetic peptide corresponding to Human Wnt2/IRP (internal sequence). A synthetic 15 amino acid peptide corresponding to residues within Human Wnt2/ IRP (NP_003382.1).
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Positive control
- Human brain tissue (cerebellum).
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab150608 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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IHC-P |
Use a concentration of 10 - 15 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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Notes |
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ELISA
Use at an assay dependent concentration. |
IHC-P
Use a concentration of 10 - 15 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. -
Tissue specificity
Expressed in brain in the thalamus, in fetal and adult lung and in placenta. -
Sequence similarities
Belongs to the Wnt family. -
Cellular localization
Secreted > extracellular space > extracellular matrix. - Information by UniProt
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Database links
- Entrez Gene: 493672 Cat
- Entrez Gene: 417769 Chicken
- Entrez Gene: 463673 Chimpanzee
- Entrez Gene: 100411308 Common marmoset
- Entrez Gene: 493729 Cow
- Entrez Gene: 612141 Dog
- Entrez Gene: 100056092 Horse
- Entrez Gene: 7472 Human
see all -
Form
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. -
Alternative names
- Int 1 related protein antibody
- Int-1-like protein 1 antibody
- Int-1-related protein antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab150608 has been referenced in 2 publications.
- Zhou D et al. Tubule-Derived Wnts Are Required for Fibroblast Activation and Kidney Fibrosis. J Am Soc Nephrol 28:2322-2336 (2017). PubMed: 28336721
- Chu EY et al. Full Spectrum of Postnatal Tooth Phenotypes in a Novel Irf6 Cleft Lip Model. J Dent Res 95:1265-73 (2016). PubMed: 27369589