This antibody is specific for both Wnt3 and Wnt3a based on the fact that the immunogen sequence is 100% identical for both.
WBmore details Unsuitable for:
ICC/IF,IHC-P or IP
Mouse, Rat, Human
Synthetic peptide within Human Wnt3 and Wnt3a aa 150-250 (Cysteine residue). The exact sequence is proprietary. SwissProt: P56703 and P56704 Database link: P56704
CHO cells transfected with Human Wnt3a.
This antibody was developed as part of a collaboration with Karl Willert’s lab from the University of California at San Diego.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.
We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.
Proto-oncogene Wnt-3: Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.
Protein Wnt-3a: Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.
Guo F et al. The action mechanism of lncRNA-HOTAIR on the drug resistance of non-small cell lung cancer by regulating Wnt signaling pathway. Exp Ther Med15:4885-4889 (2018).
Read more (PubMed: 29805510) »