Recombinant
RabMAb

Anti-Wnt6 antibody [EPR9244] (ab154144)

Overview

  • Product name
    Anti-Wnt6 antibody [EPR9244]
    See all Wnt6 primary antibodies
  • Description
    Rabbit monoclonal [EPR9244] to Wnt6
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human Wnt6.

  • Positive control
    • HeLa, Jurkat, SH-SY5Y, C6, RAW 264.7, PC12, NIH 3T3 and Neuro 2a cell lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab154144 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 40 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function
      Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
    • Sequence similarities
      Belongs to the Wnt family.
    • Post-translational
      modifications
      Palmitoylation at Ser-228 is required for efficient binding to frizzled receptors. It is also required for subsequent palmitoylation at Cys-76. Palmitoylation is necessary for proper trafficking to cell surface.
    • Cellular localization
      Secreted > extracellular space > extracellular matrix.
    • Information by UniProt
    • Database links
    • Alternative names
      • Protein Wnt 6 antibody
      • Protein Wnt-6 antibody
      • Protein Wnt-6 precursor antibody
      • Wingless type MMTV integration site family, member 6 antibody
      • wnt 6 antibody
      • Wnt6 antibody
      • WNT6_HUMAN antibody
      see all

    Images

    • All lanes : Anti-Wnt6 antibody [EPR9244] (ab154144) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : Jurkat cell lysate
      Lane 3 : SH-SY5Y cell lysate
      Lane 4 : C6 cell lysate
      Lane 5 : RAW 264.7 cell lysate
      Lane 6 : PC12 cell lysate
      Lane 7 : NIH 3T3 cell lysate
      Lane 8 : Neuro 2a cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size: 40 kDa

    References

    This product has been referenced in:
    • Jiang Z  et al. Wnt6 influences the viability of mouse embryonic palatal mesenchymal cells via the ß-catenin pathway. Exp Ther Med 14:5339-5344 (2017). Read more (PubMed: 29285061) »

    See 1 Publication for this product

    Customer reviews and Q&As

    Mit der RabMab Aktion bekommen Sie bis zum 16. Dezember beim Kauf eines primären Antikörpers einen RabMab Antikörper kostenlos. Dafür müssen Sie nur den Folgenden Code bei der Bestellung angeben: RABMAB-XBSMF.

    Wir habe...

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    Vielen Dank für Ihre Anfrage.

    Ich habe mich nach dem WNT6 Antikörper von Epitomics für Sie erkundigt. Wir bieten diesen jetzt an unter folgender Nummer in unserem Katalog:


    https://www.abcam.com/wnt6-antibody-epr924...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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