- References (1)
Product nameWRW4, FPRL1 antagonist
DescriptionSelective FPRL1 antagonist
Biological descriptionSelective FPRL1 antagonist. Inhibits binding of agonist WKYMVm to formyl peptide receptor-like 1 (FPRL1). Inhibits intracellular calcium release, kinase activation and chemotactic cell migration towards WKYMVm.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Stock solution of up to 1mM should be done in DDW. Further dilutions can be done in any physiological buffer.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Cattaneo F et al. NADPH-oxidase-dependent reactive oxygen species mediate EGFR transactivation by FPRL1 in WKYMVm-stimulated human lung cancer cells. Free Radic Biol Med 51:1126-36 (2011). Read more (PubMed: 21708247) »
- Kim Y et al. Pituitary adenylate cyclase-activating polypeptide 27 is a functional ligand for formyl peptide receptor-like 1. J Immunol 176:2969-75 (2006). Read more (PubMed: 16493055) »
- Bae YS et al. Identification of peptides that antagonize formyl peptide receptor-like 1-mediated signaling. J Immunol 173:607-14 (2004). Read more (PubMed: 15210823) »