Key features and details
- Rabbit polyclonal to WSX-1
- Suitable for: IHC-P, Flow Cyt
- Reacts with: Mouse
- Isotype: IgG
Product nameAnti-WSX-1 antibody
See all WSX-1 primary antibodies
DescriptionRabbit polyclonal to WSX-1
Tested applicationsSuitable for: IHC-P, Flow Cytmore details
Species reactivityReacts with: Mouse
Predicted to work with: Rat, Human
- Mouse lymphoma tissue; Mouse splenocytes.
Protein previously labeled as TCCR.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 50% Glycerol, 1% BSA
Aqueous buffered solution
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab217627 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/500.|
FunctionReceptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms.
Tissue specificityHighly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. Weakly expressed in other tissues examined including heart, brain, fetal and adult lung, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine, kidney and colon. In the lymphoid system, higher level expression in CD4+ T-cell subsets than in CD8+ T-cell subsets. Also weaker expression in CD19+ B-cells and monocytes.
Sequence similaritiesBelongs to the type I cytokine receptor family. Type 2 subfamily.
Contains 3 fibronectin type-III domains.
DomainThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation.
- Information by UniProt
- Class I cytokine receptor antibody
- CRL1 antibody
- Cytokine receptor-like 1 antibody
Immunohistochemical analysis of Formalin fixed, paraffin embedded Mouse lymphoma tissue labeling WSX-1 with ab217627 at 1/200 followed by conjugation to the secondary antibody and DAB staining.
Flow cytometric analysis of Mouse splenocytes labeling WSX-1 with ab217627 at 1/100 dilution followed by a FITC conjugated secondary antibody (green) compared to control cells (blue).
ab217627 has not yet been referenced specifically in any publications.