Overview

  • Product name

  • Description

    Goat polyclonal to XAGE1
  • Host species

    Goat
  • Specificity

    This antibody is expected to recognise isoform d (NP_597673.1) only. Reported variants represent identical protein (NP_597673.1; NP_001091067.1; NP_001091074.1; NP_001091062.1; NP_001091065.1).
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide: C-

    GFGFRRQGEDNT

    (with a Cysteine residue linker), corresponding to C terminal amino acids 58-69 of Human XAGE1 Isoform D (NP_597673.1).

  • Positive control

    • IHC-P: Human Testis and Placenta tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab134805 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Tissue specificity

    In normal tissues, highly expressed in testis. Expressed also in many different types of cancers: highly expressed in breast cancer, prostate cancer and many types of lung cancers, including squamous cell carcinoma, small cell carcinoma, non-small cell carcinoma, and adenocarcinoma, as well as in Ewing's cell lines, in some Ewing's sarcoma patient samples, and in one of one alveolar rhabdomyosarcoma patient sample.
  • Sequence similarities

    Belongs to the GAGE family.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cancer/testis antigen 12.1 antibody
    • CT12.1 antibody
    • G antigen family D 2 protein antibody
    • G antigen family D member 2 antibody
    • GAGD2_HUMAN antibody
    • GAGED2 antibody
    • Protein XAGE-1 antibody
    • X antigen family, member 1 antibody
    • XAGE1A antibody
    • XAGE1B antibody
    • XAGE1C antibody
    • XAGE1D antibody
    • XAGE1E antibody
    see all

Images

  • Immunohistochemistry analysis of Formalin fixed and Paraffin Embedded (IHC-P) Human Testis tissue labelling XAGE1 with ab134805 at 3.75 µg/ml.
  • Immunohistochemistry analysis of Formalin fixed and Paraffin Embedded (IHC-P) Human Placenta tissue labelling XAGE1 with ab134805 at 3.75 µg/ml.

References

ab134805 has not yet been referenced specifically in any publications.

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