Overview

  • Product name

    Anti-XPNPEP2/mAPP antibody
    See all XPNPEP2/mAPP primary antibodies
  • Description

    Rabbit polyclonal to XPNPEP2/mAPP
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Pig
  • Immunogen

    Recombinant fragment corresponding to Human XPNPEP2/mAPP aa 286-534.
    Database link: NP_003390

  • Positive control

    • A549, HeLa, HepG2 and HCT116 cell lysates
  • General notes

     This product was previously labelled as XPNPEP2

     

Properties

Applications

Our Abpromise guarantee covers the use of ab97852 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 76 kDa.

Target

  • Function

    A metalloprotease that may play a role in the inflammatory process and other reactions produced in response to injury or infection. May also play a role in the metabolism of the vasodilator bradykinin.
  • Tissue specificity

    Expressed in kidney, lung, heart, placenta, liver, small intestine and colon. No expression in brain, skeletal muscle, pancreas, spleen, thymus, prostate, testis and ovary.
  • Involvement in disease

    Angioedema induced by ACE inhibitors
  • Sequence similarities

    Belongs to the peptidase M24B family.
  • Post-translational
    modifications

    Heavily glycosylated.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Aminoacylproline aminopeptidase antibody
    • mAmP antibody
    • mAPP antibody
    • Membrane bound aminopeptidase P antibody
    • Membrane bound AmP antibody
    • Membrane bound APP antibody
    • Membrane-bound aminopeptidase P antibody
    • Membrane-bound AmP antibody
    • Membrane-bound APP antibody
    • RP23-351G20.1 antibody
    • RP4-753P9.2 antibody
    • X Pro aminopeptidase 2 antibody
    • X prolyl aminopeptidase (aminopeptidase P) 2, membrane bound antibody
    • X-Pro aminopeptidase 2 antibody
    • Xaa Pro aminopeptidase 2 antibody
    • Xaa-Pro aminopeptidase 2 antibody
    • XPNPEP2 antibody
    • XPP2_HUMAN antibody
    see all

Images

  • Anti-XPNPEP2/mAPP antibody (ab97852) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size: 76 kDa



    7.5% SDS-PAGE.

References

This product has been referenced in:

  • Banu SK  et al. Identifying a novel role for X-prolyl aminopeptidase (Xpnpep) 2 in CrVI-induced adverse effects on germ cell nest breakdown and follicle development in rats. Biol Reprod 92:67 (2015). Read more (PubMed: 25568306) »
See 1 Publication for this product

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample
Rat Tissue sections (Ovary)
Antigen retrieval step
Enzymatic - Buffer/Enzyme Used: Protease
Permeabilization
No
Specification
Ovary
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 1µg/mL · Temperature: 22°C
Fixative
Paraformaldehyde

Dr. Sakhila Banu

Verified customer

Submitted Oct 29 2013

Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample
Rat Tissue sections (GONAD)
Antigen retrieval step
Enzymatic
Permeabilization
No
Specification
GONAD
Blocking step
Serum as blocking agent for 45 minute(s) · Concentration: 5% · Temperature: 25°C
Fixative
Formaldehyde

Abcam user community

Verified customer

Submitted Sep 23 2013

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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