Anti-XPO6 antibody (ab72333)
Key features and details
- Rabbit polyclonal to XPO6
- Suitable for: IP
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-XPO6 antibody
See all XPO6 primary antibodies -
Description
Rabbit polyclonal to XPO6 -
Host species
Rabbit -
Tested applications
Suitable for: IPmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Horse, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Xenopus laevis, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis, Platypus -
Immunogen
Synthetic peptide from a region between residue 1075 and 1125 of human XPO6, NP_055986.1.
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Positive control
- Whole cell lysate from Hela cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7
Preservative: 0.09% Sodium azide
Constituents: 1.815% Tris, 1.764% Sodium citrate, 0.021% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab72333 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IP |
Notes |
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Is unsuitable for WB. This antibody can be used for WB of enriched sources of XPO6 e.g. immunoprecipitated XPO6, but it has not performed satisfactorily on crude preparations (e.g. whole cell lysate).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Function
Mediates the nuclear export of actin and profilin-actin complexes in somatic cells. -
Sequence similarities
Belongs to the exportin family.
Contains 1 importin N-terminal domain. -
Cellular localization
Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 23214 Human
- Entrez Gene: 74204 Mouse
- Entrez Gene: 293476 Rat
- Omim: 608411 Human
- SwissProt: Q96QU8 Human
- SwissProt: Q924Z6 Mouse
- Unigene: 460468 Human
- Unigene: 235663 Mouse
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Alternative names
- Exp6 antibody
- Exportin 6 antibody
- Exportin-6 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab72333 has been referenced in 2 publications.
- McNeill MC et al. Nuclear actin regulates cell proliferation and migration via inhibition of SRF and TEAD. Biochim Biophys Acta Mol Cell Res 1867:118691 (2020). PubMed: 32119877
- Xing B et al. GLP-1 signaling suppresses menin's transcriptional block by phosphorylation in ß cells. J Cell Biol 218:855-870 (2019). PubMed: 30792230