Product nameXTP (aqueous solution), Adenylyl and guanylyl cyclase inhibitor
DescriptionAdenylyl and guanylyl cyclase inhibitor
Biological descriptionAdenylyl and guanylyl cyclase inhibitor. GTP analog. Competitively inhibits transducin-catalyzed GTP hydrolysis.
Storage instructionsStore at -20°C (desiccating conditions).
Supplied in water (100 mM)
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Yanachkov I et al. Synthesis and effect of nonhydrolyzable xanthosine triphosphate derivatives on prenylation of Rab5D136N. Mol Pharmacol 51:47-51 (1997). Read more (PubMed: 9016345) »
- Klinker JF & Seifert R Functionally nonequivalent interactions of guanosine 5'-triphosphate, inosine 5'-triphosphate, and xanthosine 5'-triphosphate with the retinal G-protein, transducin, and with Gi-proteins in HL-60 leukemia cell membranes. Biochem Pharmacol 54:551-62 (1997). Read more (PubMed: 9337071) »
- Kang C et al. Replacement of Asp333 with Asn by site-directed mutagenesis changes the substrate specificity of Escherichia coli adenylosuccinate synthetase from guanosine 5'-triphosphate to xanthosine 5'-triphosphate. J Biol Chem 269:24046-9 (1994). Read more (PubMed: 7929056) »