Overview

  • Product name

  • Description

    Rabbit polyclonal to XYLT1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human XYLT1 (internal sequence). (NM_022166).
    Database link: Q86Y38

  • Positive control

    • HEK293 cell lysate; Human fetal muscle tissue.

Properties

  • Form

    Lyophilised:Reconstitute in 200ul sterile H2O.
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.2
    Preservative: 0.02% Sodium azide
    Constituents: 98% PBS, 1% BSA
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab197193 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.
WB 1/500 - 1/1000. Predicted molecular weight: 108 kDa.

Target

  • Function

    Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes.
  • Tissue specificity

    Widely expressed. Expressed at higher level in placenta, kidney and pancreas. Weakly expressed in skeletal muscle.
  • Pathway

    Glycan metabolism; chondroitin sulfate biosynthesis.
    Glycan metabolism; heparan sulfate biosynthesis.
  • Sequence similarities

    Belongs to the glycosyltransferase 14 family. XylT subfamily.
  • Post-translational
    modifications

    Contains 7 disulfide bonds.
    N-glycosylated.
  • Cellular localization

    Endoplasmic reticulum membrane. Golgi apparatus membrane. Secreted. Some fraction is also found in the extracellular space together with chondroitin sulfate proteoglycans, suggesting that it can be secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • Beta D xylosyltransferase 1 antibody
    • O xylosyltransferase 1 antibody
    • Peptide O-xylosyltransferase 1 antibody
    • PXYLT1 antibody
    • UDP-D-xylose:proteoglycan core protein antibody
    • XT-I antibody
    • XT1 antibody
    • XTI antibody
    • Xylosyltransferase 1 antibody
    • Xylosyltransferase I antibody
    • xylosyltransferase iota antibody
    • XylT-I antibody
    • XYLT1 antibody
    • XYLT1_HUMAN antibody
    see all

Images

  • Anti-XYLT1 antibody (ab197193) at 1/500 dilution + 293 cell lysate

    Predicted band size: 108 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human fetal muscle tissue, labeling XYLT1 with ab197193 at 1/100 dilution.

References

ab197193 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab197193.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up