Anti-XYLT2 antibody (ab155193)

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Overview

  • Product name

    Anti-XYLT2 antibody
    See all XYLT2 primary antibodies

  • Description

    Rabbit polyclonal to XYLT2

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WB, ICC/IFmore details

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chicken, Cow, Dog

  • Immunogen

    Recombinant fragment, corresponding to a region within internal sequence amino acids 272-520 of Human XYLT2 (Uniprot ID: Q9H1B5).

  • Positive control

    • 293T, A431, HeLa, Raji whole cell lysate; HeLa cells

  • General notes

    Store as a concentrated solution.

Properties

Applications

Our Abpromise guarantee covers the use of ab155193 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 97 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Function

    Probably catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes (By similarity). Its enzyme activity has not been demonstrated.

  • Tissue specificity

    Widely expressed. Expressed at higher level in kidney and pancreas.

  • Pathway

    Glycan metabolism; chondroitin sulfate biosynthesis.
    Glycan metabolism; heparan sulfate biosynthesis.

  • Sequence similarities

    Belongs to the glycosyltransferase 14 family. XylT subfamily.

  • Post-translational
    modifications

    Contains disulfide bonds.

  • Cellular localization

    Endoplasmic reticulum membrane. Golgi apparatus membrane.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • Peptide O xylosyltransferase 1 antibody
    • Peptide O-xylosyltransferase 1 antibody
    • protein xylosyltransferase 2 antibody
    • PXYLT2 antibody
    • UDP-D-XYLOSE:PROTEOGLYCAN CORE PROTEIN BETA-D-XYLOSYLTRANSFERASE 2 antibody
    • UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase antibody
    • XT II antibody
    • XT-II antibody
    • XT2 antibody
    • Xylosyltransferase 2 antibody
    • Xylosyltransferase II antibody
    • xylT II antibody
    • XylT-II antibody
    • XYLT2 antibody
    • XYLT2_HUMAN antibody
    see all

Images

  • Western blot - Anti-XYLT2 antibody (ab155193)
    Western blot - Anti-XYLT2 antibody (ab155193)
    Anti-XYLT2 antibody (ab155193) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size: 97 kDa



    7.5% SDS PAGE
  • Immunocytochemistry/ Immunofluorescence - Anti-XYLT2 antibody (ab155193)
    Immunocytochemistry/ Immunofluorescence - Anti-XYLT2 antibody (ab155193)
    Immunofluorescent analysis of methanol-fixed HeLa cells labeling XYLT2 with ab155193 at 1/500 dilution (green). Alpha tubulin filaments were labeled red.

References

ab155193 has not yet been referenced specifically in any publications.

Publishing research using ab155193? Please let us know so that we can cite the reference in this datasheet.

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