• Product name
    Anti-Y14 antibody - N-terminal
    See all Y14 primary antibodies
  • Description
    Rabbit polyclonal to Y14 - N-terminal
  • Host species
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Human, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within N-terminal amino acids 13-62 of Rat Y14 (NP_001258067.1).

  • Positive control
    • Rat stomach lysate.



Our Abpromise guarantee covers the use of ab167467 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 19 kDa.


  • Function
    Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction in the mature mRNA and thereby influences downstream processes of gene expression including mRNA splicing, nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). The heterodimer MAGOH-RBM8A interacts with PYM that function to enhance the translation of EJC-bearing spliced mRNAs by recruiting them to the ribosomal 48S preinitiation complex. Remains associated with mRNAs in the cytoplasm until the mRNAs engage the translation machinery. Its removal from cytoplasmic mRNAs requires translation initiation from EJC-bearing spliced mRNAs. Associates preferentially with mRNAs produced by splicing. Does not interact with pre-mRNAs, introns, or mRNAs produced from intronless cDNAs. Associates with both nuclear mRNAs and newly exported cytoplasmic mRNAs. Complex with MAGOH is a component of the nonsense mediated decay (NMD) pathway.
  • Tissue specificity
  • Sequence similarities
    Belongs to the RBM8A family.
    Contains 1 RRM (RNA recognition motif) domain.
  • Cellular localization
    Nucleus. Nucleus speckle. Cytoplasm. Nucleocytoplasmic shuttling protein. Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA. Colocalizes with the core EJC, THOC4, NXF1 and UAP56 in the nucleus and nuclear speckles.
  • Information by UniProt
  • Database links
  • Alternative names
    • Binder of OVCA1 1 antibody
    • Binder of OVCA1-1 antibody
    • BOV 1 antibody
    • BOV 1A antibody
    • BOV 1B antibody
    • BOV 1C antibody
    • BOV-1 antibody
    • BOV1 antibody
    • BOV1A antibody
    • BOV1B antibody
    • BOV1C antibody
    • HSPC 114 antibody
    • HSPC114 antibody
    • MDS 014 antibody
    • MDS014 antibody
    • RBM 8 antibody
    • RBM 8A antibody
    • RBM 8B antibody
    • RBM8 antibody
    • rbm8a antibody
    • RBM8A_HUMAN antibody
    • RBM8B antibody
    • Ribonucleoprotein RBM 8 antibody
    • Ribonucleoprotein RBM 8A antibody
    • Ribonucleoprotein RBM8 antibody
    • Ribonucleoprotein RBM8A antibody
    • RNA binding motif protein 8 antibody
    • RNA binding motif protein 8A antibody
    • RNA binding motif protein 8B antibody
    • RNA binding protein 8A antibody
    • RNA binding protein Y14 antibody
    • RNA-binding motif protein 8A antibody
    • RNA-binding protein 8A antibody
    • RNA-binding protein Y14 antibody
    • ZNRP antibody
    • ZRNP 1 antibody
    • ZRNP1 antibody
    see all


  • Anti-Y14 antibody - N-terminal (ab167467) at 1 µg/ml + Rat stomach lysate at 10 µg

    Predicted band size: 19 kDa


ab167467 has not yet been referenced specifically in any publications.

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