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ab52771 has been referenced in 77 publications.

  • Rausch V  et al. The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae. Curr Biol 29:242-255.e6 (2019). PubMed: 30595521
  • Zhao W  et al. Limonin attenuates the stemness of cervical carcinoma cells by promoting YAP nuclear-cytoplasmic translocation. Food Chem Toxicol 125:621-628 (2019). PubMed: 30738134
  • Lim S  et al. Identification of the kinase STK25 as an upstream activator of LATS signaling. Nat Commun 10:1547 (2019). PubMed: 30948712
  • Zhou J  et al. Yap-Hippo promotes A549 lung cancer cell death via modulating MIEF1-related mitochondrial stress and activating JNK pathway. Biomed Pharmacother 113:108754 (2019). PubMed: 30875659
  • Chen L  et al. USF1-induced upregulation of LINC01048 promotes cell proliferation and apoptosis in cutaneous squamous cell carcinoma by binding to TAF15 to transcriptionally activate YAP1. Cell Death Dis 10:296 (2019). PubMed: 30931936
  • Yoshida M  et al. miR-7977 inhibits the Hippo-YAP signaling pathway in bone marrow mesenchymal stromal cells. PLoS One 14:e0213220 (2019). PubMed: 30835743
  • Guo C  et al. LATS2 inhibits cell proliferation and metastasis through the Hippo signaling pathway in glioma. Oncol Rep 41:2753-2761 (2019). PubMed: 30896861
  • Fu L  et al. Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis. PLoS Biol 17:e3000201 (2019). PubMed: 30933975
  • Su X  et al. ELK1-induced upregulation of long non-coding RNA MIR100HG predicts poor prognosis and promotes the progression of osteosarcoma by epigenetically silencing LATS1 and LATS2. Biomed Pharmacother 109:788-797 (2019). PubMed: 30551532
  • Rausch V & Hansen CG Immunofluorescence Study of Endogenous YAP in Mammalian Cells. Methods Mol Biol 1893:97-106 (2019). PubMed: 30565128
  • Li B  et al. c-Abl regulates YAPY357 phosphorylation to activate endothelial atherogenic responses to disturbed flow. J Clin Invest 129:1167-1179 (2019). PubMed: 30629551
  • Shen Y  et al. S1P/S1PR3 axis promotes aerobic glycolysis by YAP/c-MYC/PGAM1 axis in osteosarcoma. EBioMedicine N/A:N/A (2018). PubMed: 30587459
  • Liu MX  et al. Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma. Oncogene 37:1637-1653 (2018). PubMed: 29335519
  • Lin X  et al. AP2a enhanced the osteogenic differentiation of mesenchymal stem cells by inhibiting the formation of YAP/RUNX2 complex and BARX1 transcription. Cell Prolif N/A:e12522 (2018). PubMed: 30443989
  • Ibar C  et al. Tension-dependent regulation of mammalian Hippo signaling through LIMD1. J Cell Sci 131:N/A (2018). PubMed: 29440237
  • Gao F  et al. STARD13 is positively correlated with good prognosis and enhances 5-FU sensitivity via suppressing cancer stemness in hepatocellular carcinoma cells. Onco Targets Ther 11:5371-5381 (2018). PubMed: 30214243
  • Eales KL  et al. Verteporfin selectively kills hypoxic glioma cells through iron-binding and increased production of reactive oxygen species. Sci Rep 8:14358 (2018). PubMed: 30254296
  • Zhang X  et al. circRNA_104075 stimulates YAP-dependent tumorigenesis through the regulation of HNF4a and may serve as a diagnostic marker in hepatocellular carcinoma. Cell Death Dis 9:1091 (2018). PubMed: 30361504
  • Tao Y  et al. Huaier Augmented the Chemotherapeutic Sensitivity of Oxaliplatin via Downregulation of YAP in Hepatocellular Carcinoma. J Cancer 9:3962-3970 (2018). PubMed: 30410600
  • Cho YS  et al. Regulation of Yki/Yap subcellular localization and Hpo signaling by a nuclear kinase PRP4K. Nat Commun 9:1657 (2018). PubMed: 29695716
  • Zhu HY  et al. Long non-coding RNA UCA1 desensitizes breast cancer cells to trastuzumab by impeding miR-18a repression of Yes-associated protein 1. Biochem Biophys Res Commun 496:1308-1313 (2018). WB . PubMed: 29408336
  • Yuan X  et al. Metformin inhibits glioma cells stemness and epithelial-mesenchymal transition via regulating YAP activity. Biomed Pharmacother 102:263-270 (2018). WB ; Human . PubMed: 29567539
  • Pu X  et al. COPB2 promotes cell proliferation and tumorigenesis through up-regulating YAP1 expression in lung adenocarcinoma cells. Biomed Pharmacother 103:373-380 (2018). WB . PubMed: 29674272
  • Cao C  et al. Bidirectional juxtacrine ephrinB2/Ephs signaling promotes angiogenesis of ECs and maintains self-renewal of MSCs. Biomaterials 172:1-13 (2018). WB . PubMed: 29709731
  • Zhang B  et al. Hypoxia-inducible factor-1 promotes cancer progression through activating AKT/Cyclin D1 signaling pathway in osteosarcoma. Biomed Pharmacother 105:1-9 (2018). WB . PubMed: 29807229
  • Chitragari G  et al. Regulation of Yes-Associated Protein by Laminar Flow. Ann Vasc Surg N/A:N/A (2018). PubMed: 29758328
  • Pan Y  et al. RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer. Mol Cancer 17:102 (2018). PubMed: 30037330
  • Gao L  et al. LncRNA THOR attenuates cisplatin sensitivity of nasopharyngeal carcinoma cells via enhancing cells stemness. Biochimie 152:63-72 (2018). PubMed: 29959065
  • Er EE  et al. Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization. Nat Cell Biol 20:966-978 (2018). PubMed: 30038252
  • Molina L  et al. Hepatocyte-Derived Lipocalin 2 Is a Potential Serum Biomarker Reflecting Tumor Burden in Hepatoblastoma. Am J Pathol 188:1895-1909 (2018). PubMed: 29920228
  • Yuan B  et al. WDR1 Promotes Cell Growth and Migration and Contributes to Malignant Phenotypes of Non-small Cell Lung Cancer through ADF/cofilin-mediated Actin Dynamics. Int J Biol Sci 14:1067-1080 (2018). PubMed: 29989053
  • Lin J  et al. Neuropilin 1 (NRP1) is a novel tumor marker in hepatocellular carcinoma. Clin Chim Acta 485:158-165 (2018). PubMed: 29966621
  • Qin J  et al. Tanshinone IIA inhibits cervix carcinoma stem cells migration and invasion via inhibiting YAP transcriptional activity. Biomed Pharmacother 105:758-765 (2018). PubMed: 29909343
  • Kang W  et al. miR-375 is involved in Hippo pathway by targeting YAP1/TEAD4-CTGF axis in gastric carcinogenesis. Cell Death Dis 9:92 (2018). WB, IP . PubMed: 29367737
  • Zhang X  et al. The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis. Nat Commun 8:15280 (2017). WB, IP, IF, IHC-P ; Human . PubMed: 28474680
  • Lin XJ  et al. hsa-miR-485-5p reverses epithelial to mesenchymal transition and promotes cisplatin-induced cell death by targeting PAK1 in oral tongue squamous cell carcinoma. Int J Mol Med 40:83-89 (2017). WB ; Human . PubMed: 28535002
  • Mesrouze Y  et al. Dissection of the interaction between the intrinsically disordered YAP protein and the transcription factor TEAD. Elife 6:N/A (2017). PubMed: 28430104
  • Zhu G  et al. 12-O-Tetradecanoylphorbol-13-acetate (TPA) is anti-tumorigenic in liver cancer cells via inhibiting YAP through AMOT. Sci Rep 7:44940 (2017). PubMed: 28322318
  • Crook ZR  et al. Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets. Nat Commun 8:2244 (2017). PubMed: 29269835
  • Fisher ML  et al. Inhibition of YAP function overcomes BRAF inhibitor resistance in melanoma cancer stem cells. Oncotarget 8:110257-110272 (2017). PubMed: 29299145
  • Shan L  et al. Huaier Restrains Proliferative and Migratory Potential of Hepatocellular Carcinoma Cells Partially Through Decreased Yes-Associated Protein 1. J Cancer 8:4087-4097 (2017). PubMed: 29187885
  • Zheng Y  et al. The extracellular vesicles secreted by lung cancer cells in radiation therapy promote endothelial cell angiogenesis by transferring miR-23a. PeerJ 5:e3627 (2017). WB ; Human . PubMed: 28852584
  • Ma X  et al. Hippo signaling promotes JNK-dependent cell migration. Proc Natl Acad Sci U S A 114:1934-1939 (2017). PubMed: 28174264
  • Chia S  et al. Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time. Nat Commun 8:435 (2017). PubMed: 28874669
  • Zhang J  et al. Circular RNA_LARP4 inhibits cell proliferation and invasion of gastric cancer by sponging miR-424-5p and regulating LATS1 expression. Mol Cancer 16:151 (2017). PubMed: 28893265
  • Foster CT  et al. Mutual dependence of the MRTF-SRF and YAP-TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamics. Genes Dev 31:2361-2375 (2017). PubMed: 29317486
  • Chorzalska A  et al. Long-Term Exposure to Imatinib Mesylate Downregulates Hippo Pathway and Activates YAP in a Model of Chronic Myelogenous Leukemia. Stem Cells Dev 26:656-677 (2017). PubMed: 28103766
  • Dieffenbach PB  et al. Arterial stiffness induces remodeling phenotypes in pulmonary artery smooth muscle cells via YAP/TAZ-mediated repression of cyclooxygenase-2. Am J Physiol Lung Cell Mol Physiol 313:L628-L647 (2017). PubMed: 28642262
  • Pei Y  et al. FGF8 promotes cell proliferation and resistance to EGFR inhibitors via upregulation of EGFR in human hepatocellular carcinoma cells. Oncol Rep 38:2205-2210 (2017). PubMed: 28791365
  • Zhou Y  et al. TEAD1/4 exerts oncogenic role and is negatively regulated by miR-4269 in gastric tumorigenesis. Oncogene 36:6518-6530 (2017). WB . PubMed: 28759040
  • Li P  et al. Elevated expression of Nodal and YAP1 is associated with poor prognosis of gastric adenocarcinoma. J Cancer Res Clin Oncol 142:1765-73 (2016). WB . PubMed: 27325246
  • Ruan T  et al. MicroRNA-186 targets Yes-associated protein 1 to inhibit Hippo signaling and tumorigenesis in hepatocellular carcinoma. Oncol Lett 11:2941-2945 (2016). PubMed: 27073580
  • Qin L  et al. 14-3-3s regulation of and interaction with YAP1 in acquired gemcitabine resistance via promoting ribonucleotide reductase expression. Oncotarget 7:17726-36 (2016). PubMed: 26894857
  • Song Y  et al. Activated Hippo/Yes-Associated Protein Pathway Promotes Cell Proliferation and Anti-apoptosis in Endometrial Stromal Cells of Endometriosis. J Clin Endocrinol Metab 101:1552-61 (2016). PubMed: 26977530
  • Ye L  et al. Cardiomyocytes in Young Infants With Congenital Heart Disease: a Three-Month Window of Proliferation. Sci Rep 6:23188 (2016). WB, IF . PubMed: 26976548
  • Hansen CG  et al. The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1. Cell Res 25:1299-313 (2015). PubMed: 26611634
  • Kang W  et al. Targeting of YAP1 by microRNA-15a and microRNA-16-1 exerts tumor suppressor function in gastric adenocarcinoma. Mol Cancer 14:52 (2015). WB . PubMed: 25743273
  • Shen Z & Stanger BZ YAP regulates S-phase entry in endothelial cells. PLoS One 10:e0117522 (2015). PubMed: 25635998
  • Ye L  et al. Decreased Yes-Associated Protein-1 (YAP1) Expression in Pediatric Hearts with Ventricular Septal Defects. PLoS One 10:e0139712 (2015). PubMed: 26426694
  • Stein C  et al. YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers. PLoS Genet 11:e1005465 (2015). WB, IP, ChIP ; Human . PubMed: 26295846
  • Ma B  et al. Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase. Nat Cell Biol 17:95-103 (2015). PubMed: 25438054
  • Whiteman EL  et al. Crumbs3 is essential for proper epithelial development and viability. Mol Cell Biol 34:43-56 (2014). Mouse . PubMed: 24164893
  • Dixit D  et al. Chaetocin-induced ROS-mediated apoptosis involves ATM-YAP1 axis and JNK-dependent inhibition of glucose metabolism. Cell Death Dis 5:e1212 (2014). WB ; Human . PubMed: 24810048
  • Wang J  et al. Mutual interaction between YAP and CREB promotes tumorigenesis in liver cancer. Hepatology N/A:N/A (2013). Human . PubMed: 23532963
  • Michaloglou C  et al. The tyrosine phosphatase PTPN14 is a negative regulator of YAP activity. PLoS One 8:e61916 (2013). ICC/IF . PubMed: 23613971
  • Xiao W  et al. Mutual interaction between YAP and c-Myc is critical for carcinogenesis in liver cancer. Biochem Biophys Res Commun 439:167-72 (2013). WB, IHC ; Human . PubMed: 23994632
  • Sun G & Irvine KD Ajuba family proteins link JNK to Hippo signaling. Sci Signal 6:ra81 (2013). PubMed: 24023255
  • Li S  et al. Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts. Cell Rep 4:1116-30 (2013). WB ; Human . PubMed: 24055055
  • Wang J  et al. Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in liver cancer. J Biol Chem 288:33667-81 (2013). WB ; Human . PubMed: 24089522
  • Yang S  et al. CDK1 phosphorylation of YAP promotes mitotic defects and cell motility and is essential for neoplastic transformation. Cancer Res 73:6722-33 (2013). IP . PubMed: 24101154
  • Tanaka I  et al. LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade. Oncogene N/A:N/A (2013). PubMed: 24336325
  • Li L  et al. MEK1 promotes YAP and their interaction is critical for tumorigenesis in liver cancer. FEBS Lett 587:3921-7 (2013). IHC ; Human . PubMed: 24211253
  • Fujii M  et al. TGF-ß synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth. J Exp Med 209:479-94 (2012). WB ; Human . PubMed: 22329991
  • Sheen-Chen SM  et al. Yes-associated protein is not an independent prognostic marker in breast cancer. Anticancer Res 32:3321-5 (2012). PubMed: 22843909
  • Murakami H  et al. LATS2 is a tumor suppressor gene of malignant mesothelioma. Cancer Res 71:873-83 (2011). WB, ICC/IF, IHC-P ; Human . PubMed: 21245096
  • Kang W  et al. Yes-associated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis. Clin Cancer Res 17:2130-9 (2011). IHC . PubMed: 21346147
  • Cai J  et al. The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program. Genes Dev 24:2383-8 (2010). PubMed: 21041407

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