Overview

  • Product name
  • Description
    Rabbit polyclonal to Yes1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Chicken, Cow, Dog, Xenopus laevis, Zebrafish, Xenopus tropicalis
  • Immunogen

    Recombinant protein fragment corresponding to a region within amino acids 234-531 of Human Yes1

  • Positive control
    • 293T, A431, H1299, HeLa, HepG2, Raji and NIH 3T3 whole cell lysates, HeLa cells

Properties

Applications

Our Abpromise guarantee covers the use of ab152108 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 60 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Function
    Promotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46.
  • Sequence similarities
    Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH2 domain.
    Contains 1 SH3 domain.
  • Post-translational
    modifications
    Autophosphorylated.
  • Cellular localization
    Cytoplasm > cytosol. In epithelial cells infected with Neisseria gonorrhoeae, forms aggregates beneath bacterial microcolonies.
  • Information by UniProt
  • Database links
  • Form
    This protein is known to be similar in amino acid sequence to HCK (P08631), LCK (P06239), FYN (P06241), SRC (P12931), and LYN (P07948). Therefore, cross-reactivity with these homologous proteins may be observed. We would be happy to provide immunogen alignment information upon request.
  • Alternative names
    • c Yes antibody
    • Cellular Yes 1 protein antibody
    • Cellular Yes1 protein antibody
    • HsT441 antibody
    • P61 YES antibody
    • p61-Yes antibody
    • Proto oncogene tyrosine protein kinase YES antibody
    • Proto-oncogene c-Yes antibody
    • Tyrosine-protein kinase Yes antibody
    • v yes 1 Yamaguchi sarcoma viral oncogene homolog 1 antibody
    • Viral oncogene yes 1 homolog 1 antibody
    • Viral oncogene yes1 homolog 1 antibody
    • Yamaguchi sarcoma oncogene antibody
    • Yes 1 antibody
    • Yes antibody
    • YES proto oncogene 1, Src family tyrosine kinase antibody
    • YES_HUMAN antibody
    • YES1 antibody
    • YES1 proto oncogene, Src family tyrosine kinase antibody
    see all

Images

  • Anti-Yes1 antibody (ab152108) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size: 60 kDa



    7.5% SDS PAGE
  • Anti-Yes1 antibody (ab152108) at 1/1000 dilution + NIH 3T3 whole cell lysate at 30 µg

    Predicted band size: 60 kDa



    7.5% SDS PAGE
  • Immunofluorescence analysis of methanol-fixed HeLa cells labeling Yes1 using ab152108 at a 1/200 dilution. lower image is costained with hoechst 33342.

References

ab152108 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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