Overview

  • Product name
    Anti-Yes1 antibody [EPR3172]
    See all Yes1 primary antibodies
  • Description
    Rabbit monoclonal [EPR3172] to Yes1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IPmore details
    Unsuitable for: Flow Cyt,ICC or IHC-P
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human Yes1 aa 1-100 (internal sequence). The exact sequence is proprietary.

  • Positive control
    • U87-MG, Molt-4, LnCaP and A431 cell lysates
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab133314 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 60 kDa.
IP 1/10 - 1/100.
  • Application notes
    Is unsuitable for Flow Cyt,ICC or IHC-P.
  • Target

    • Function
      Promotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46.
    • Sequence similarities
      Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
      Contains 1 protein kinase domain.
      Contains 1 SH2 domain.
      Contains 1 SH3 domain.
    • Post-translational
      modifications
      Autophosphorylated.
    • Cellular localization
      Cytoplasm > cytosol. In epithelial cells infected with Neisseria gonorrhoeae, forms aggregates beneath bacterial microcolonies.
    • Information by UniProt
    • Database links
    • Form
      This protein is known to be similar in amino acid sequence to HCK (P08631), LCK (P06239), FYN (P06241), SRC (P12931), and LYN (P07948). Therefore, cross-reactivity with these homologous proteins may be observed. We would be happy to provide immunogen alignment information upon request.
    • Alternative names
      • c Yes antibody
      • Cellular Yes 1 protein antibody
      • Cellular Yes1 protein antibody
      • HsT441 antibody
      • P61 YES antibody
      • p61-Yes antibody
      • Proto oncogene tyrosine protein kinase YES antibody
      • Proto-oncogene c-Yes antibody
      • Tyrosine-protein kinase Yes antibody
      • v yes 1 Yamaguchi sarcoma viral oncogene homolog 1 antibody
      • Viral oncogene yes 1 homolog 1 antibody
      • Viral oncogene yes1 homolog 1 antibody
      • Yamaguchi sarcoma oncogene antibody
      • Yes 1 antibody
      • Yes antibody
      • YES proto oncogene 1, Src family tyrosine kinase antibody
      • YES_HUMAN antibody
      • YES1 antibody
      • YES1 proto oncogene, Src family tyrosine kinase antibody
      see all

    Images

    • All lanes : Anti-Yes1 antibody [EPR3172] (ab133314) at 1/1000 dilution

      Lane 1 : U87-MG cell lysate
      Lane 2 : Molt-4 cell lysate
      Lane 3 : LnCaP cell lysate
      Lane 4 : A431 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 60 kDa

    References

    ab133314 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab133314.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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