Recombinant
RabMAb

Recombinant Anti-Yes1 antibody [EPR3173] - BSA and Azide free (ab239964)

Overview

  • Product name

    Anti-Yes1 antibody [EPR3173] - BSA and Azide free
    See all Yes1 primary antibodies
  • Description

    Rabbit monoclonal [EPR3173] to Yes1 - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, ICC, IP, WBmore details
    Unsuitable for: Flow Cyt
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Yes1 aa 500-600. The exact sequence is proprietary.

  • General notes

    Ab239964 is the carrier-free version of ab109265. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    ab239964 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

Properties

Applications

Our Abpromise guarantee covers the use of ab239964 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC Use at an assay dependent concentration.
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Detects a band of approximately 60 kDa (predicted molecular weight: 61 kDa).
  • Application notes
    Is unsuitable for Flow Cyt.
  • Target

    • Function

      Promotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46.
    • Sequence similarities

      Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
      Contains 1 protein kinase domain.
      Contains 1 SH2 domain.
      Contains 1 SH3 domain.
    • Post-translational
      modifications

      Autophosphorylated.
    • Cellular localization

      Cytoplasm > cytosol. In epithelial cells infected with Neisseria gonorrhoeae, forms aggregates beneath bacterial microcolonies.
    • Information by UniProt
    • Database links

    • Form

      This protein is known to be similar in amino acid sequence to HCK (P08631), LCK (P06239), FYN (P06241), SRC (P12931), and LYN (P07948). Therefore, cross-reactivity with these homologous proteins may be observed. We would be happy to provide immunogen alignment information upon request.
    • Alternative names

      • c Yes antibody
      • Cellular Yes 1 protein antibody
      • Cellular Yes1 protein antibody
      • HsT441 antibody
      • P61 YES antibody
      • p61-Yes antibody
      • Proto oncogene tyrosine protein kinase YES antibody
      • Proto-oncogene c-Yes antibody
      • Tyrosine-protein kinase Yes antibody
      • v yes 1 Yamaguchi sarcoma viral oncogene homolog 1 antibody
      • Viral oncogene yes 1 homolog 1 antibody
      • Viral oncogene yes1 homolog 1 antibody
      • Yamaguchi sarcoma oncogene antibody
      • Yes 1 antibody
      • Yes antibody
      • YES proto oncogene 1, Src family tyrosine kinase antibody
      • YES_HUMAN antibody
      • YES1 antibody
      • YES1 proto oncogene, Src family tyrosine kinase antibody
      see all

    Images

    • ab109265 at 1/50 dilution staining Yes1 in Human colon by Immunohistochemistry, Paraffin-embedded tissue.

      This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab109265).

      Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    References

    ab239964 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab239964.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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