Overview

  • Product name

    Anti-YKL-40/CHI3L1 antibody [MM0628-9X24]
    See all YKL-40/CHI3L1 primary antibodies
  • Description

    Rat monoclonal [MM0628-9X24] to YKL-40/CHI3L1
  • Host species

    Rat
  • Tested applications

    Suitable for: ELISAmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human YKL-40/CHI3L1.

  • General notes

    Previously labelled as CHI3L1

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    Constituent: 100% PBS
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    ab135148 is purified from tissue culture supernatant.
  • Clonality

    Monoclonal
  • Clone number

    MM0628-9X24
  • Isotype

    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab135148 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000 - 1/2000.

Target

  • Function

    Carbohydrate-binding lectin with a preference for chitin. May play a role in defense against pathogens, or in tissue remodeling. May play an important role in the capacity of cells to respond to and cope with changes in their environment.
  • Tissue specificity

    Present in activated macrophages, articular chondrocytes, synovial cells as well as in liver. Undetectable in muscle tissues, lung, pancreas, mononuclear cells, or fibroblasts.
  • Involvement in disease

    A genetic variation in CHI3L1 is associated with susceptibility to asthma-related traits type 7 (ASRT7) [MIM:611960]. Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing and dyspnea, bronchial hyperresponsiveness (BHR) as assessed by methacholine challenge test, serum IgE levels, atopy, and atopic dermatitis.
  • Sequence similarities

    Belongs to the glycosyl hydrolase 18 family.
  • Post-translational
    modifications

    Glycosylated.
  • Cellular localization

    Secreted > extracellular space.
  • Information by UniProt
  • Database links

  • Alternative names

    • 39 kDa synovial protein antibody
    • ASRT7 antibody
    • Cartilage glycoprotein 39 antibody
    • CGP-39 antibody
    • CGP39 antibody
    • CH3L1_HUMAN antibody
    • CHI3L1 antibody
    • chitinase 3 like 1 (cartilage glycoprotein 39) antibody
    • chitinase 3 like 1 antibody
    • Chitinase 3 like protein 1 precursor antibody
    • chitinase antibody
    • Chitinase-3-like protein 1 antibody
    • Chondrocyte protein YKL40 antibody
    • GP 39 antibody
    • GP-39 antibody
    • GP39 antibody
    • HC gp39 antibody
    • HCGP 3P antibody
    • hCGP-39 antibody
    • HCgp39 antibody
    • YKL 40 antibody
    • YKL-40 antibody
    • YKL40 antibody
    • YYL 40 antibody
    see all

References

ab135148 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab135148.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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