Key features and details
- Rabbit polyclonal to YKT6
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-YKT6 antibody
See all YKT6 primary antibodies
DescriptionRabbit polyclonal to YKT6
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow
Recombinant fragment corresponding to Human YKT6 aa 10-195.
YKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSSKGTRASV KEQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVLDEFSKQVDRID WPVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDETKIILHNTMES LLERGEKLDDLVSKSEVLGTQSKAFYKTARKQNSCC
Database link: O15498-1
- WB: A549 whole cell lysate. IHC-P: Human adrenal gland tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Constituents: 50% Glycerol, PBS, 0.03% Proclin 300
Concentration information loading...
PurityProtein G purified
Purification notesPurity >95%.
Our Abpromise guarantee covers the use of ab236583 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 22 kDa.|
|IHC-P||1/20 - 1/200.|
FunctionVesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.
Sequence similaritiesBelongs to the synaptobrevin family.
Contains 1 longin domain.
Contains 1 v-SNARE coiled-coil homology domain.
DomainThe longin domain regulates palmitoylation and membrane targeting.
modificationsPalmitoylated; catalyzes its own palmitoylation. Palmitoylation is required for Golgi targeting.
Farnesylation is required for Golgi targeting.
Cellular localizationCytoplasm > cytosol. Cytoplasmic vesicle membrane. Golgi apparatus membrane. Probably cycles through vesicles between Golgi and endosomes.
- Information by UniProt
- R SNARE antibody
- SNARE protein Ykt6 antibody
- Synaptobrevin homolog YKT6 antibody
Anti-YKT6 antibody (ab236583) at 1/500 dilution + A549 (Human lung carcinoma cell line) whole cell lysate
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 22 kDa
Paraffin-embedded human adrenal gland tissue stained for YKT6 with ab236583 at 1/100 dilution in immunohistochemical analysis.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab236583 has not yet been referenced specifically in any publications.