Overview

  • Product name

    Anti-YPEL3 antibody - N-terminal
  • Description

    Rabbit polyclonal to YPEL3 - N-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human YPEL3 (N terminal). It consists of a 15 amino acid peptide near the amino terminus end.
    Database link: P61236

  • Positive control

    • Human prostate tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab174788 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 14 kDa.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Involved in proliferation and apoptosis in myeloid precursor cells.
  • Tissue specificity

    Widely expressed.
  • Sequence similarities

    Belongs to the yippee family.
  • Post-translational
    modifications

    Probably ubiquitinated leading to its degradation by the proteasome.
  • Cellular localization

    Nucleus > nucleolus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Protein yippee-like 3 antibody
    • Small ubiquitinated apoptotic protein antibody
    • Yippee like 3 antibody
    • Yippee-like 3 (Drosophila) antibody
    • Ypel3 antibody
    • YPEL3_HUMAN antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human prostate tissue, labeling YPEL3 using ab174788 at 2.5 µg/ml.

References

This product has been referenced in:

  • Zhang J  et al. YPEL3 suppresses epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/ß-catenin signaling pathway. J Exp Clin Cancer Res 35:109 (2016). Read more (PubMed: 27400785) »
See 1 Publication for this product

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