Overview

  • Product name
    Z-ATAD-FMK
  • Description
    Caspase-12 inhibitor
  • Biological description
    Specific caspase-12 inhibitor. Suppresses annular cell apoptosis and caspase-9 activity in vitro. Active in vitro and in vivo.
  • Purity
    > 95%

Properties

References

This product has been referenced in:
  • Zhang YH  et al. Cyclic stretch-induced apoptosis in rat annulus fibrosus cells is mediated in part by endoplasmic reticulum stress through nitric oxide production. Eur Spine J 20:1233-43 (2011). Read more (PubMed: 21336971) »
  • Zhao CQ  et al. Both endoplasmic reticulum and mitochondria are involved in disc cell apoptosis and intervertebral disc degeneration in rats. Age (Dordr) 32:161-77 (2010). Read more (PubMed: 19960285) »
  • Kim SM  et al. Mollugin induces apoptosis in human Jurkat T cells through endoplasmic reticulum stress-mediated activation of JNK and caspase-12 and subsequent activation of mitochondria-dependent caspase cascade regulated by Bcl-xL. Toxicol Appl Pharmacol 241:210-20 (2009). Read more (PubMed: 19716835) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab141383.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

Sign up