Zafirlukast (Accolate), 5-lipoxygenase inhibitor  (ab143038)

Overview

  • Product name

    Zafirlukast (Accolate), 5-lipoxygenase inhibitor 
  • Description

    5-lipoxygenase inhibitor and CysLT1 antagonist
  • Biological description

    5-lipoxygenase inhibitor and CysLT1 antagonist. Attenuates CNS infiltration of inflammatory cells, shows antiasthmatic and anti-inflammatory effects in vivo. Orally active.
  • Purity

    > 99%
  • CAS Number

    107753-78-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Singh RK  et al. A review on leukotrienes and their receptors with reference to asthma. J Asthma 50:922-31 (2013). Read more (PubMed: 23859232) »
  • Bastos EM  et al. Effect of zafirlukast on capsular contracture around silicone implants in rats. Acta Cir Bras 27:1-6 (2012). Read more (PubMed: 22159431) »
  • Wang L  et al. Antiasthmatic drugs targeting the cysteinyl leukotriene receptor 1 alleviate central nervous system inflammatory cell infiltration and pathogenesis of experimental autoimmune encephalomyelitis. J Immunol 187:2336-45 (2011). Read more (PubMed: 21804021) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab143038.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up