Recombinant
RabMAb

Anti-ZAN antibody [EPR11209] (ab170925)

Overview

  • Product name
    Anti-ZAN antibody [EPR11209]
  • Description
    Rabbit monoclonal [EPR11209] to ZAN
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Human
    Does not react with: Rat
  • Immunogen

    Synthetic peptide within Human ZAN aa 2050-2150 (Cysteine residue). The exact sequence is proprietary.
    Database link: Q9Y493

  • Positive control
    • Mouse testis lysate.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR11209
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab170925 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 306 kDa.
  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Function
      Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling.
    • Tissue specificity
      In testis, primarily in haploid spermatids.
    • Sequence similarities
      Contains 1 EGF-like domain.
      Contains 3 MAM domains.
      Contains 4 TIL (trypsin inhibitory-like) domains.
      Contains 5 VWFC domains.
      Contains 4 VWFD domains.
    • Domain
      The MAM domains probably mediate sperm adhesion to the zona pellucida.
      During sperm migration through the reproductive tracts, the mucin-like domain might inhibit inappropriate trapping of spermatozoa or promoting adhesion to the oviductal isthmus.
      The VWFD domain 2 may mediate covalent oligomerization.
    • Cellular localization
      Cell membrane. Exclusively on the apical region of the sperm head.
    • Information by UniProt
    • Database links
    • Alternative names
      • OTTHUMP00000211358 antibody
      • OTTHUMP00000211359 antibody
      • OTTHUMP00000211360 antibody
      • OTTHUMP00000211361 antibody
      • OTTHUMP00000211362 antibody
      • OTTHUMP00000211363 antibody
      • ZAN antibody
      • ZAN_HUMAN antibody
      • Zonadhesin antibody
      see all

    Images

    • Anti-ZAN antibody [EPR11209] (ab170925) at 1/1000 dilution + Mouse testis lysate at 10 µg

      Secondary
      Goat anti-rabbit HRP conjugate at 1/2000 dilution

      Predicted band size: 306 kDa

    References

    ab170925 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab170925.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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