
Recombinant Anti-ZAN antibody [EPR11209] (ab170925)
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Overview
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Product name
Anti-ZAN antibody [EPR11209]
See all ZAN primary antibodies -
Description
Rabbit monoclonal [EPR11209] to ZAN -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: ICC,IHC-P or IP -
Species reactivity
Reacts with: Mouse, Human
Does not react with: Rat -
Immunogen
Synthetic peptide within Human ZAN aa 2050-2150 (Cysteine residue). The exact sequence is proprietary.
Database link: Q9Y493 -
Positive control
- Mouse testis lysate.
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General notes
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.
This product is a recombinant rabbit monoclonal antibody.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant -
Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPR11209 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab170925 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | 1/1000 - 1/10000. Predicted molecular weight: 306 kDa. |
Target
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Function
Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling. -
Tissue specificity
In testis, primarily in haploid spermatids. -
Sequence similarities
Contains 1 EGF-like domain.
Contains 3 MAM domains.
Contains 4 TIL (trypsin inhibitory-like) domains.
Contains 5 VWFC domains.
Contains 4 VWFD domains. -
Domain
The MAM domains probably mediate sperm adhesion to the zona pellucida.
During sperm migration through the reproductive tracts, the mucin-like domain might inhibit inappropriate trapping of spermatozoa or promoting adhesion to the oviductal isthmus.
The VWFD domain 2 may mediate covalent oligomerization. -
Cellular localization
Cell membrane. Exclusively on the apical region of the sperm head. - Information by UniProt
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Database links
- Entrez Gene: 7455 Human
- Entrez Gene: 22635 Mouse
- Omim: 602372 Human
- SwissProt: Q9Y493 Human
- SwissProt: O88799 Mouse
- Unigene: 307004 Human
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Alternative names
- OTTHUMP00000211358 antibody
- OTTHUMP00000211359 antibody
- OTTHUMP00000211360 antibody
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Images
Protocols
Datasheets and documents
References
ab170925 has not yet been referenced specifically in any publications.