Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR11209] to ZAN
- Suitable for: WB
- Reacts with: Mouse, Human
Product nameAnti-ZAN antibody [EPR11209]
See all ZAN primary antibodies
DescriptionRabbit monoclonal [EPR11209] to ZAN
Tested applicationsSuitable for: WBmore details
Unsuitable for: ICC,IHC-P or IP
Species reactivityReacts with: Mouse, Human
Does not react with: Rat
Synthetic peptide within Human ZAN aa 2050-2150 (Cysteine residue). The exact sequence is proprietary.
Database link: Q9Y493
- Mouse testis lysate.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant
Concentration information loading...
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab170925 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/10000. Predicted molecular weight: 306 kDa.|
FunctionBinds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling.
Tissue specificityIn testis, primarily in haploid spermatids.
Sequence similaritiesContains 1 EGF-like domain.
Contains 3 MAM domains.
Contains 4 TIL (trypsin inhibitory-like) domains.
Contains 5 VWFC domains.
Contains 4 VWFD domains.
DomainThe MAM domains probably mediate sperm adhesion to the zona pellucida.
During sperm migration through the reproductive tracts, the mucin-like domain might inhibit inappropriate trapping of spermatozoa or promoting adhesion to the oviductal isthmus.
The VWFD domain 2 may mediate covalent oligomerization.
Cellular localizationCell membrane. Exclusively on the apical region of the sperm head.
- Information by UniProt
- OTTHUMP00000211358 antibody
- OTTHUMP00000211359 antibody
- OTTHUMP00000211360 antibody
ab170925 has not yet been referenced specifically in any publications.