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Rabbit polyclonal to ZCCHV
Recombinant fragment, corresponding to a region within internal sequence amino acids 401-721 of Human ZCCHV (UniProt Q7Z2W4).
A431 whole cell lysate; A431 cells; Human hepatoma tissue.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/5000 - 1/20000. Predicted molecular weight: 101 kDa.
1/100 - 1/1000.
1/100 - 1/1000.
Induces an innate immunity to viral infections by preventing the accumulation of viral RNAs in the cytoplasm. Seems to recruit the RNA processing exosome to degrade the target RNAs. Inhibits alphavirus and filovirus replication.
Contains 4 C3H1-type zinc fingers.
Contains 1 PARP catalytic domain. Contains 1 WWE domain.
The second and fourth zinc fingers are involved in binding to specific viral RNAs.
Cytoplasm. Nucleus. Localizes in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner.
Information by UniProt
ADP ribosyltransferase diphtheria toxin like 13 antibody
Western blot - Anti-ZCCHV antibody (ab154680)
Anti-ZCCHV antibody (ab154680) at 1/10000 dilution + A431 whole cell lysate at 30 µg
Predicted band size: 101 kDa 7.5% SDS PAGE
Immunocytochemistry/ Immunofluorescence - Anti-ZCCHV antibody (ab154680)
Immunofluorescent analysis of paraformaldehyde-fixed A431 cells labeling ZCCHV with ab154680 at 1/200 dilution. Lower panel is co-stained with Hoechst 33342.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZCCHV antibody (ab154680)
Immunohistochemical analysis of paraffin-embedded Human hepatoma tissue labeling ZCCHV with ab154680 at 1/500 dilution.
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