Key features and details
- Mixed potent, nonsteroidal ERα and ERβ ligand. Mycotoxin.
- CAS Number: 17924-92-4
- Purity: > 98%
- Form / State: Solid
- Source: Fusarium sp.
Product nameZearalenone (ZEA), ERalpha and ERbeta ligand
DescriptionMixed potent, nonsteroidal ERα and ERβ ligand. Mycotoxin.
Biological descriptionMixed potent, nonsteroidal ERα and ERβ ligand (IC50 values are 56 and 41 nM for ERα and ERβ respectively). Shows agonist effects at lower doses. Partially selective for ERα activation. Induces apoptosis in male germ cells. Active in vivo.
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab142473 has been referenced in 1 publication.
- Xu Y et al. Protective Effects of Melatonin Against Zearalenone Toxicity on Porcine Embryos in vitro. Front Pharmacol 10:327 (2019). PubMed: 31024301