• Product name

    Anti-Zinc finger antiviral protein antibody
    See all Zinc finger antiviral protein primary antibodies
  • Description

    Rabbit polyclonal to Zinc finger antiviral protein
  • Host species

  • Specificity

    ab105357 is predicted to not crossreact with other ZAP members. Four isoforms of Zinc finger antiviral protein are known to exist.
  • Tested applications

    Suitable for: ICC/IF, WB, ICCmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human Zinc finger antiviral protein (C terminal).
    Database link: NP_078901

  • Positive control

    • WB: HeLa cell lysate ICC: HeLa cells


  • Form

  • Storage instructions

    Shipped at 4°C. Store at +4°C.
  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

  • Isotype

  • Research areas


Our Abpromise guarantee covers the use of ab105357 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 101 kDa.
ICC Use a concentration of 20 µg/ml.


  • Function

    Induces an innate immunity to viral infections by preventing the accumulation of viral RNAs in the cytoplasm. Seems to recruit the RNA processing exosome to degrade the target RNAs. Inhibits alphavirus and filovirus replication.
  • Sequence similarities

    Contains 4 C3H1-type zinc fingers.
    Contains 1 PARP catalytic domain.
    Contains 1 WWE domain.
  • Domain

    The second and fourth zinc fingers are involved in binding to specific viral RNAs.
  • Cellular localization

    Cytoplasm. Nucleus. Localizes in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner.
  • Information by UniProt
  • Database links

  • Alternative names

    • ADP ribosyltransferase diphtheria toxin like 13 antibody
    • ARTD13 antibody
    • FLB6421 antibody
    • PARP13 antibody
    • ZAP antibody
    • ZC3H2 antibody
    • ZC3HAV 1 antibody
    • Zc3hav1 antibody
    • ZC3HDC 2 antibody
    • ZC3HDC2 antibody
    • ZCCHV antibody
    • ZCCHV_HUMAN antibody
    • Zinc finger antiviral protein antibody
    • Zinc finger CCCH domain containing protein 2 antibody
    • Zinc finger CCCH domain-containing antiviral protein 1 antibody
    • Zinc finger CCCH domain-containing protein 2 antibody
    • Zinc finger CCCH type antiviral 1 antibody
    • Zinc finger CCCH type antiviral protein 1 antibody
    • Zinc finger CCCH-type antiviral protein 1 antibody
    see all


  • Anti-Zinc finger antiviral protein antibody (ab105357) at 1 µg/ml + HeLa cell lysate at 15 µg

    Predicted band size: 101 kDa

  • Immunocytochemical analysis of Zinc finger antiviral protein in HeLa cells stained with ab105357 at 20 µg/ml.

  • Immunofluorescence of ZC3HAV1 in Hela cells using ab105357 at 20 ug/ml.


This product has been referenced in:

  • Lee H  et al. Zinc-finger antiviral protein mediates retinoic acid inducible gene I-like receptor-independent antiviral response to murine leukemia virus. Proc Natl Acad Sci U S A 110:12379-84 (2013). Read more (PubMed: 23836649) »
See 1 Publication for this product

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