Overview

  • Product name
    Zinpyr-1, Fluorogenic Zn2+ reporter
  • Description
    Cell-permeable fluorogenic Zn2+ reporter
  • Biological description
    Cell-permeable fluorogenic Zn2+ reporter. 2,7-Dichlorofluorescein (ab146332) derivative. Induces positive fluorescence upon metal ion complexation. PET sensor.
  • Purity
    > 95%
  • CAS Number
    288574-78-7
  • Chemical structure
    Chemical Structure

Properties

  • Excitation
    515nm
  • Emission
    515nm
  • Chemical name
    4′,5′-Bis[bis(2-pyridylmethyl)aminomethyl]-2′,7′-dichlorofluorescein
  • Molecular weight
    823.72
  • Molecular formula
    C46H36Cl2N6O5
  • Storage instructions
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    Oc8c(CN(Cc1ccccn1)Cc2ccccn2)c9Oc5c(CN(Cc3ccccn3)Cc4ccccn4)c(O)c(Cl)cc5C7(OC(=O)c6ccccc67)c9cc8Cl
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:
  • Figueroa JA  et al. Selectivity and specificity of small molecule fluorescent dyes/probes used for the detection of Zn2+ and Ca2+ in cells. Metallomics 6:301-15 (2014). Read more (PubMed: 24356796) »
  • Goldsmith CR & Lippard SJ Analogues of Zinpyr-1 provide insight into the mechanism of zinc sensing. Inorg Chem 45:6474-8 (2006). Read more (PubMed: 16878961) »
  • Malavolta M  et al. Single and three-color flow cytometry assay for intracellular zinc ion availability in human lymphocytes with Zinpyr-1 and double immunofluorescence: relationship with metallothioneins. Cytometry A 69:1043-53 (2006). Read more (PubMed: 16998866) »
See all 2 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab145349.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up