Zinquin ethyl ester, Zn2+ selective fluorescent probe (ab145478)

Overview

  • Product name

    Zinquin ethyl ester, Zn2+ selective fluorescent probe
  • Description

    Cell-permeable Zn2+ selective fluorescent probe
  • Biological description

    Cell-permeable Zn2+ selective fluorescent probe. Zinquin (ab145451) precursor. Labels micromolar concentrations of intracellular Zn2+ ions with an intense extranuclear fluorescence emitting in the blue range.

  • Purity

    > 99%
  • CAS Number

    181530-09-6
  • Chemical structure

    Chemical Structure

Properties

  • Excitation

    368nm
  • Emission

    490nm
  • Chemical name

    Ethyl 2-[2-methyl-8-[(4-methylphenyl)sulfonylamino]quinolin-6-yl]oxyacetate
  • Molecular weight

    414.47
  • Molecular formula

    C21H22N2O5S
  • PubChem identifier

    3638243
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCOC(=O)COC1=CC(=C2C(=C1)C=CC(=N2)C)NS(=O)(=O)C3=CC=C(C=C3)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Nowakowski AB & Petering DH Reactions of the fluorescent sensor, Zinquin, with the zinc-proteome: adduct formation and ligand substitution. Inorg Chem 50:10124-33 (2011). Read more (PubMed: 21905645) »
  • Rachidi W  et al. Prion protein protects against zinc-mediated cytotoxicity by modifying intracellular exchangeable zinc and inducing metallothionein expression. J Trace Elem Med Biol 23:214-23 (2009). Read more (PubMed: 19486831) »
  • Helmersson A  et al. The level of free intracellular zinc mediates programmed cell death/cell survival decisions in plant embryos. Plant Physiol 147:1158-67 (2008). Read more (PubMed: 18508953) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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