Overview

  • Product name

  • Description

    Rabbit polyclonal to ZIP-4
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment corresponding to Human ZIP-4 aa 23-327.
    Database link: Q6P5W5

  • Positive control

    • WB: Mouse stomach lysate; HEK-293T whole cell lysate. IHC-P: Human kidney tissue.
  • General notes

    Protein previously labeled as SLC39A4.

Properties

Applications

Our Abpromise guarantee covers the use of ab230099 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 68 kDa.
IHC-P 1/20 - 1/200.

Target

  • Function

    Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability.
  • Tissue specificity

    Highly expressed in kidney, small intestine, stomach, colon, jejunum and duodenum.
  • Involvement in disease

    Acrodermatitis enteropathica, zinc-deficiency type
  • Sequence similarities

    Belongs to the ZIP transporter (TC 2.A.5) family.
  • Cellular localization

    Cell membrane. Recycling endosome membrane. Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability.
  • Information by UniProt
  • Database links

  • Alternative names

    • 1600025H15Rik antibody
    • Acrodermatitis enteropathica zinc deficiency type antibody
    • Activated in W/Wv mouse stomach 2 antibody
    • AEZ antibody
    • AU041686 antibody
    • AWMS2 antibody
    • FLJ20327 antibody
    • MGC156705 antibody
    • MGC74741 antibody
    • S39A4_HUMAN antibody
    • Slc39a4 antibody
    • Solute carrier family 39 member 4 antibody
    • Ssolute carrier family 39 zinc transporter member 4 antibody
    • Zinc transporter ZIP4 antibody
    • ZIP-4 antibody
    • ZIP4 antibody
    • Zrt and Irt like protein 4 antibody
    • Zrt- and Irt-like protein 4 antibody
    see all

Images

  • All lanes : Anti-ZIP-4 antibody (ab230099) at 1/1000 dilution

    Lane 1 : Mouse stomach lysate
    Lane 2 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate

    Secondary
    All lanes : Goat polyclonal to rabbit IgG at 1/10000 dilution

    Predicted band size: 68 kDa

  • Paraffin-embedded human kidney tissue stained for ZIP-4 using ab230099 at 1/100 dilution in immunohistochemical analysis.

References

ab230099 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab230099.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up